This thesis is composed of four peer-reviewed publications on which I was first author and a commentary on those publications. In the commentary, I critique and comment on these four papers. I present the commentary in two parts. In the first part, I reflect on the strengths, weaknesses, and research contributions of each paper and I reflect on how each paper has contributed to the overarching research theme of healthcare worker reactions and responses to public health interventions and if and how context might influence these reactions. In the second part, I reflect on the importance of understanding healthcare worker reactions to public health interventions and if and how this has been explored in the literature. I suggest a new approach to examining the influence of context on healthcare worker reactions and responses to public health interventions, supported by findings from my papers. In part 1 of the commentary, I 1) explain the research concepts and approaches for each paper and why the research choices were made; 2) discuss the impact and relevance of each paper in its field at the time of publication; 3) critique the methods of each paper and discuss how they could have been improved upon to better understand the research questions that they addressed at the time; and 4) briefly discuss the relevance of the paper now, and comment on how the same research questions could be addressed now. I then comment on how the included papers have influenced my personal research interests, highlighting how the papers illustrate my journey in understanding healthcare workers, their reactions to the interventions they are asked to implement, and the role of context in influencing these reactions. In Part 2 of the commentary, I expand on the contributions of each paper to my personal research interest by reflecting on findings from my papers as well as the current evidence on this topic. I discuss the different domains of healthcare worker reactions demonstrated in my papers and link these to the literature on healthcare workers, specifically describing the gaps in evidence about the impacts on healthcare workers in intervention evaluation. In this section, I draw on learnings from other frameworks that have sought to understand effective health intervention delivery, as well as those that describe context. I suggest a framework for 5 understanding how different layers of context work together to influence healthcare workers and conclude with a suggestion for next steps and for the wider applicability of the findings from my studies. I also include a reflection on my positionality and how this has shaped my interpretations within the papers in this thesis and throughout the commentary.