Jindani, Amina; Atwine, Daniel; Grint, Daniel; Bah, Boubacar; Adams, Jack; Ticona, Eduardo Rómulo; Shrestha, Bhabana; Agizew, Tefera; Hamid, Saeed; Jamil, Bushra; +35 more... Byamukama, Adolf; Kananura, Keneth; Mugisha Taremwa, Ivan; Bonnet, Maryline; Camara, Lansana Mady; Bah-Sow, Oumou Younoussa; Bah, Kindy Sadio; Bah, Nene Mamata; Sow, Maimouna; Ticona Huaroto, César Eduardo; Mugruza Pineda, Raquel; Tandukar, Bijesh; Raya, Bijendra Bhakta; Shrestha, Neko; Mathoma, Anikie; Mathebula-Modongo, Unami P; Basotli, Joyce; Irfan, Muhammad; Begum, Dilshad; Muzammil, Ammara; Ahmed, Imran; Hasan, Rumina; Burgos, Marcos V; Sultan, Faisal; Hassan, Mariam; Masood, Iqra; Robb, Claire; Decker, Jonathan; Grubnic, Sisa; Butcher, Philip D; Witney, Adam; Dhillon, Jasvir; Munshi, Tulika; Fielding, Katherine; Harrison, Thomas S; (2023) Four-Month High-Dose Rifampicin Regimens for Pulmonary Tuberculosis. NEJM evidence, 2 (9). EVIDoa2300054-. ISSN 2766-5526 DOI: https://doi.org/10.1056/EVIDoa2300054
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Abstract
High-Dose Rifampicin Regimen for Pulmonary TuberculosisThis randomized, controlled trial tested the efficacy and safety of high-dose rifampicin (1200 or 1800 mg/d) as part of the treatment regimen for pulmonary tuberculosis. Four-month high-dose rifampicin regimens had no dose-limiting side effects but failed to meet noninferiority criteria compared with the standard 6-month control regimen.
Item Type | Article |
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Faculty and Department | Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology & International Health (2023-) |
PubMed ID | 38320155 |
Elements ID | 214850 |
Official URL | http://dx.doi.org/10.1056/evidoa2300054 |
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