New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany.

Fabian Heinrich ORCID logo ; Tobias Huter ; Sophie Mertens ; Philine Lange ; Jessica Vering ; Axel Heinemann ; Dominik Sebastian Nörz ; Armin Hoffmann ; Martin Aepfelbacher ; Benjamin Ondruschka ; +2 more... Susanne Krasemann ; Marc Lütgehetmann ; (2023) New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany. Emerging infectious diseases, 29 (3). pp. 652-656. ISSN 1080-6040 DOI: 10.3201/eid2903.221297
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We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.


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