Emergence of Novel Norovirus GII.4 Variant.

Chhabra, Preeti; Tully, Damien CORCID logo; Mans, Janet; Niendorf, Sandra; Barclay, Leslie; Cannon, Jennifer L; Montmayeur, Anna M; Pan, Chao-Yang; Page, Nicola; Williams, Rachel; +14 more...Tutill, Helena; Roy, Sunando; Celma, Cristina; Beard, Stuart; Mallory, Michael L; Manouana, Gédéon Prince; Velavan, Thirumalaisamy P; Adegnika, Ayola Akim; Kremsner, Peter G; Lindesmith, Lisa C; Hué, Stéphane; Baric, Ralph S; Breuer, Judith; and Vinjé, Jan (2024) Emergence of Novel Norovirus GII.4 Variant. Emerging infectious diseases, 30 (1). pp. 163-167. ISSN 1080-6040 DOI: 10.3201/eid3001.231003
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We detected a novel GII.4 variant with an amino acid insertion at the start of epitope A in viral protein 1 of noroviruses from the United States, Gabon, South Africa, and the United Kingdom collected during 2017-2022. Early identification of GII.4 variants is crucial for assessing pandemic potential and informing vaccine development.


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