Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial.

Joseph N Jarvis ORCID logo ; Roger Chou ; Thomas S Harrison ; David S Lawrence ORCID logo ; Charles Muthoga ; Kennedy Mupeli ; David B Meya ; Henry C Mwandumba ; Cecilia Kanyama ; Graeme Meintjes ; +7 more... Tshepo B Leeme ; Chiratidzo E Ndhlovu ; Pauline Beattie ; Omar Sued ; Carmen Pérez Casas ; Michael Makanga ; Nathan Ford ; (2023) Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial. The Lancet Global health, 11 (11). e1688-e1690. ISSN 2214-109X DOI: 10.1016/S2214-109X(23)00412-6
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Translating evidence from clinical trials to routine care can take many years, particularly in low-income and middle-income countries, delaying access to lifesaving or life-changing treatments. As few as one in five evidence-based health interventions are incorporated into routine use, and the average time lag between evidence availability and practice change is up to 17 years.


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