Influence of Landscape Patterns on Exposure to Lassa Fever Virus, Guinea.

Stephanie Longet ; Cristina Leggio ; Joseph Akoi Bore ; Stephanie Key ; Tom Tipton ; Yper Hall ; Fara Raymond Koundouno ; Hilary Bower ORCID logo ; Tapan Bhattacharyya ; N'Faly Magassouba ; +6 more... Stephan Günther ; Ana-Maria Henao-Restrapo ; Jeremy S Rossman ; Mandy Kader Konde ; Kimberly Fornace ; Miles W Carroll ; (2023) Influence of Landscape Patterns on Exposure to Lassa Fever Virus, Guinea. Emerging infectious diseases, 29 (2). pp. 304-313. ISSN 1080-6040 DOI: 10.3201/eid2902.212525
Copy

Lassa fever virus (LASV) is the causative agent of Lassa fever, a disease endemic in West Africa. Exploring the relationships between environmental factors and LASV transmission across ecologically diverse regions can provide crucial information for the design of appropriate interventions and disease monitoring. We investigated LASV exposure in 2 ecologically diverse regions of Guinea. Our results showed that exposure to LASV was heterogenous between and within sites. LASV IgG seropositivity was 11.9% (95% CI 9.7%-14.5%) in a coastal study site in Basse-Guinée, but it was 59.6% (95% CI 55.5%-63.5%) in a forested study site located in Guinée Forestière. Seropositivity increased with age in the coastal site. We also found significant associations between exposure risk for LASV and landscape fragmentation in coastal and forested regions. Our study highlights the potential link between environmental change and LASV emergence and the urgent need for research on land management practices that reduce disease risks.


picture_as_pdf
Longet-etal-2023-Influence-of-landscape-patterns-on.pdf
subject
Published Version
Available under Creative Commons: Attribution 4.0

View Download

Atom BibTeX OpenURL ContextObject in Span Multiline CSV OpenURL ContextObject Dublin Core Dublin Core MPEG-21 DIDL Data Cite XML EndNote HTML Citation JSON MARC (ASCII) MARC (ISO 2709) METS MODS RDF+N3 RDF+N-Triples RDF+XML RIOXX2 XML Reference Manager Refer Simple Metadata ASCII Citation EP3 XML
Export

Downloads