Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018.
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Savita
Lasrado
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Paul H
Lee
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Shanshan
Li
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Xuefeng
Liu
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Afshin
Maleki
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Preeti
Malik
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Mohammad Ali
Mansournia
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Francisco Rogerlândio
Martins-Melo
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Walter
Mendoza
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Ritesh G
Menezes
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Endalkachew Worku
Mengesha
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Tuomo J
Meretoja
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Tomislav
Mestrovic
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Andreea
Mirica
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Babak
Moazen
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Osama
Mohamad
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Yousef
Mohammad
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Abdollah
Mohammadian-Hafshejani
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Reza
Mohammadpourhodki
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Salahuddin
Mohammed
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Shafiu
Mohammed
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Ali H
Mokdad
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Masoud
Moradi
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Paula
Moraga
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Sumaira
Mubarik
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Getaneh Baye B
Mulu
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Lillian
Mwanri
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Ahamarshan Jayaraman
Nagarajan
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Mukhammad David
Naimzada
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Muhammad
Naveed
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Javad
Nazari
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Rawlance
Ndejjo
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Ionut
Negoi
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Frida N
Ngalesoni
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Georges
Nguefack-Tsague
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Josephine W
Ngunjiri
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Cuong Tat
Nguyen
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Huong Lan Thi
Nguyen
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Chukwudi A
Nnaji
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Jean Jacques
Noubiap
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Virginia
Nuñez-Samudio
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Vincent Ebuka
Nwatah
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Bogdan
Oancea
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Oluwakemi Ololade
Odukoya
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Andrew T
Olagunju
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Babayemi Oluwaseun
Olakunde
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Bolajoko Olubukunola
Olusanya
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Jacob Olusegun
Olusanya
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Ahmed Omar
Bali
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Obinna E
Onwujekwe
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Orish Ebere
Orisakwe
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Nikita
Otstavnov
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Stanislav S
Otstavnov
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Mayowa O
Owolabi
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PA
Mahesh
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Jagadish Rao
Padubidri
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Adrian
Pana
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Ashok
Pandey
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Seithikurippu R
Pandi-Perumal
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Fatemeh Pashazadeh
Kan
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George C
Patton
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Shrikant
Pawar
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Emmanuel K
Peprah
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Maarten J
Postma
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Liliana
Preotescu
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Zahiruddin Quazi
Syed
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Navid
Rabiee
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Amir
Radfar
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Alireza
Rafiei
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Fakher
Rahim
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Vafa
Rahimi-Movaghar
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Amir Masoud
Rahmani
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Kiana
Ramezanzadeh
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Juwel
Rana
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Chhabi Lal
Ranabhat
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Sowmya J
Rao
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David Laith
Rawaf
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Salman
Rawaf
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Reza
Rawassizadeh
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Lemma Demissie
Regassa
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Nima
Rezaei
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Aziz
Rezapour
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Mavra A
Riaz
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Ana Isabel
Ribeiro
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Jennifer M
Ross
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Enrico
Rubagotti
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Susan Fred
Rumisha
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Godfrey M
Rwegerera
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Sahar Saeedi
Moghaddam
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Rajesh
Sagar
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Biniyam
Sahiledengle
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Maitreyi
Sahu
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Marwa Rashad
Salem
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Hossein Samadi
Kafil
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Abdallah M
Samy
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Benn
Sartorius
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Brijesh
Sathian
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Abdul-Aziz
Seidu
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Amira A
Shaheen
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Masood Ali
Shaikh
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Morteza
Shamsizadeh
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Wondimeneh Shibabaw
Shiferaw
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Jae Il
Shin
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Roman
Shrestha
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Jasvinder A
Singh
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Valentin Yurievich
Skryabin
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Anna Aleksandrovna
Skryabina
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Shahin
Soltani
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Mu'awiyyah Babale
Sufiyan
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Takahiro
Tabuchi
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Eyayou Girma
Tadesse
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Nuno
Taveira
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Fisaha Haile
Tesfay
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Rekha
Thapar
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Marcos Roberto
Tovani-Palone
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Gebiyaw Wudie
Tsegaye
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Chukwuma David
Umeokonkwo
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Bhaskaran
Unnikrishnan
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Jorge Hugo
Villafañe
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Francesco S
Violante
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Bay
Vo
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Giang Thu
Vu
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Yohannes Dibaba
Wado
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Yasir
Waheed
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Richard G
Wamai
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Yanzhong
Wang
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Paul
Ward
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Nuwan Darshana
Wickramasinghe
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Katherine
Wilson
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Sanni
Yaya
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Paul
Yip
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Naohiro
Yonemoto
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Chuanhua
Yu
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Mikhail Sergeevich
Zastrozhin
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Yunquan
Zhang
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Zhi-Jiang
Zhang
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Simon I
Hay
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Laura
Dwyer-Lindgren
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Local Burden of Disease sub-Saharan Africa HIV Prevalence Collab
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(2022)
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018.
BMC medicine, 20 (1).
488-.
ISSN 1741-7015
DOI: 10.1186/s12916-022-02639-z
BACKGROUND: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustainable Development Goals (SDGs). Precise HIV burden information is critical for effective geographic and epidemiological targeting of prevention and treatment interventions. Age- and sex-specific HIV prevalence estimates are widely available at the national level, and region-wide local estimates were recently published for adults overall. We add further dimensionality to previous analyses by estimating HIV prevalence at local scales, stratified into sex-specific 5-year age groups for adults ages 15-59 years across SSA. METHODS: We analyzed data from 91 seroprevalence surveys and sentinel surveillance among antenatal care clinic (ANC) attendees using model-based geostatistical methods to produce estimates of HIV prevalence across 43 countries in SSA, from years 2000 to 2018, at a 5 × 5-km resolution and presented among second administrative level (typically districts or counties) units. RESULTS: We found substantial variation in HIV prevalence across localities, ages, and sexes that have been masked in earlier analyses. Within-country variation in prevalence in 2018 was a median 3.5 times greater across ages and sexes, compared to for all adults combined. We note large within-district prevalence differences between age groups: for men, 50% of districts displayed at least a 14-fold difference between age groups with the highest and lowest prevalence, and at least a 9-fold difference for women. Prevalence trends also varied over time; between 2000 and 2018, 70% of all districts saw a reduction in prevalence greater than five percentage points in at least one sex and age group. Meanwhile, over 30% of all districts saw at least a five percentage point prevalence increase in one or more sex and age group. CONCLUSIONS: As the HIV epidemic persists and evolves in SSA, geographic and demographic shifts in prevention and treatment efforts are necessary. These estimates offer epidemiologically informative detail to better guide more targeted interventions, vital for combating HIV in SSA.
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