Brown, Michael; Saund, Jasjot; Qureshi, Azka; Plowright, Megan; Drury, Katie; Gahir, Joshua; Simpson, Tom; Newman, Thomas; Adams, Kate; Galloway, James; +7 more... Durairaj, Kezia; Elgizouli, Kamla; Rampling, Tommy; Cole, Joby; Easom, Nicholas; Goodman, Anna L; Marks, Michael; (2022) Demographics and Outcomes of Initial Phase of COVID-19 Medicines Delivery Units Across 4 UK Centers During Peak B1.1.529 Omicron Epidemic: A Service Evaluation. Open forum infectious diseases, 9 (10). ofac527-. ISSN 2328-8957 DOI: https://doi.org/10.1093/ofid/ofac527
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Abstract
BACKGROUND: COVID-19 medicines delivery units (CMDU) were established in late December 2021 to deliver early antiviral therapy to patients classified as at risk with the aim of preventing hospitalization. METHODS: We performed a service evaluation at 4 CMDUs in England. We assessed demographics and triage outcomes of CMDU referral, uptake of antiviral therapy, and the rate of subsequent hospitalizations within 2 weeks of CMDU referral. RESULTS: Over a 3-week period, 4788 patients were referred and 3989 were ultimately assessed by a CMDU. Overall, 832 of the patients referred (17%) were judged eligible for treatment and 628 (13%) were ultimately prescribed an antiviral agent. The overall rate of admission within 14 days was 1%. Patients who were admitted were significantly older than those who did not require hospitalization. Of patients prescribed molnupiravir and sotrovimab, 1.8% and 3.2%, respectively, were admitted. CONCLUSIONS: There was a high volume of referrals to CMDU service during the initial surge of the Omicron wave in the United Kingdom. A minority of patients were judged to be eligible for therapy. In a highly vaccinated population, the overall hospitalization rate was low.
Item Type | Article |
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Faculty and Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
Research Centre | Covid-19 Research |
PubMed ID | 36320201 |
Elements ID | 196231 |
Official URL | http://dx.doi.org/10.1093/ofid/ofac527 |
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Filename: Brown_etal_2022_Demographics-and-outcomes-of-initial.pdf
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