Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries.

Erin Rottinghaus Romano ; Katrina Sleeman ; Patricia Hall-Eidson ; Clement Zeh ; Ravikiran Bhairavabhotla ; Guoqing Zhang ; Amitabh Adhikari ; George Alemnji ; Yolanda Rebello Cardo ; Ana Pinheiro ; +45 more... Barbara Pocongo ; Laura T Eno ; Judith D Shang ; Clement B Ndongmo ; Hilda Rosario ; Orquidea Moreno ; Lucia Aurora De La Cruz De León ; Peter Fonjungo ; Constantin Kabwe ; Steve Ahuke-Mundeke ; Dan Gama ; Sindisiwe Dlamini ; Gugu Maphalala ; Tefsay Abreha ; Anne Purfield ; Yared Tedla Gebrehiwot ; Daniel Melese Desalegn ; Frank Basiye ; Jane Mwangi ; Nancy Bowen ; Yohannes Mengistu ; Shirley Lecher ; Elizabeth Kampira ; Muluken Kaba ; Joseph Bitilinyu-Bangoh ; Gillian Masamha ; Sofia Omar Viegas ; R Suzanne Beard ; Gerhard van Rooyen ; Andreas N Shiningavamwe ; McPaul I J ; Nnaemeka C Iriemenam ; Nwando Mba ; Catherine Okoi ; Joel Katoro ; Dennis L Kenyi ; Bior K Bior ; Christina Mwangi ; Susan Nabadda ; Pontiano Kaleebu ORCID logo ; Samuel L Yingst ; Prisca Chikwanda ; Levi Veri ; Raivi Simbi ; Heather Alexander ; (2022) Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries. Emerging infectious diseases, 28 (13). S59-S68. ISSN 1080-6040 DOI: 10.3201/eid2813.220789
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The US President's Emergency Plan for AIDS Relief (PEPFAR) supports molecular HIV and tuberculosis diagnostic networks and information management systems in low- and middle-income countries. We describe how national programs leveraged these PEPFAR-supported laboratory resources for SARS-CoV-2 testing during the COVID-19 pandemic. We sent a spreadsheet template consisting of 46 indicators for assessing the use of PEPFAR-supported diagnostic networks for COVID-19 pandemic response activities during April 1, 2020, to March 31, 2021, to 27 PEPFAR-supported countries or regions. A total of 109 PEPFAR-supported centralized HIV viral load and early infant diagnosis laboratories and 138 decentralized HIV and TB sites reported performing SARS-CoV-2 testing in 16 countries. Together, these sites contributed to >3.4 million SARS-CoV-2 tests during the 1-year period. Our findings illustrate that PEPFAR-supported diagnostic networks provided a wide range of resources to respond to emergency COVID-19 diagnostic testing in 16 low- and middle-income countries.


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