Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries.

Romano, ER; Sleeman, K; Hall-Eidson, P; Zeh, C; Bhairavabhotla, R; Zhang, G; Adhikari, A; Alemnji, G; Cardo, YR; Pinheiro, A; +45 more...Pocongo, B; Eno, LT; Shang, JD; Ndongmo, CB; Rosario, H; Moreno, O; De León, Lucia Aurora De La Cruz; Fonjungo, P; Kabwe, C; Ahuke-Mundeke, S; Gama, D; Dlamini, S; Maphalala, G; Abreha, T; Purfield, A; Gebrehiwot, YT; Desalegn, DM; Basiye, F; Mwangi, J; Bowen, N; Mengistu, Y; Lecher, S; Kampira, E; Kaba, M; Bitilinyu-Bangoh, J; Masamha, G; Viegas, SO; Beard, RS; van Rooyen, G; Shiningavamwe, AN; I J, M; Iriemenam, NC; Mba, N; Okoi, C; Katoro, J; Kenyi, DL; Bior, BK; Mwangi, C; Nabadda, S; Kaleebu, PORCID logo; Yingst, SL; Chikwanda, P; Veri, L; Simbi, R; Alexander, H and (2022) Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries. Emerging infectious diseases, 28 (13). S59-S68. ISSN 1080-6040 DOI: 10.3201/eid2813.220789
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The US President's Emergency Plan for AIDS Relief (PEPFAR) supports molecular HIV and tuberculosis diagnostic networks and information management systems in low- and middle-income countries. We describe how national programs leveraged these PEPFAR-supported laboratory resources for SARS-CoV-2 testing during the COVID-19 pandemic. We sent a spreadsheet template consisting of 46 indicators for assessing the use of PEPFAR-supported diagnostic networks for COVID-19 pandemic response activities during April 1, 2020, to March 31, 2021, to 27 PEPFAR-supported countries or regions. A total of 109 PEPFAR-supported centralized HIV viral load and early infant diagnosis laboratories and 138 decentralized HIV and TB sites reported performing SARS-CoV-2 testing in 16 countries. Together, these sites contributed to >3.4 million SARS-CoV-2 tests during the 1-year period. Our findings illustrate that PEPFAR-supported diagnostic networks provided a wide range of resources to respond to emergency COVID-19 diagnostic testing in 16 low- and middle-income countries.


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