Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment.
Antimycobacterial Susceptibility Testing Group;
(2022)
Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment.
European Respiratory Journal, 59 (4).
p. 2200166.
ISSN 0903-1936
DOI: https://doi.org/10.1183/13993003.00166-2022
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Inappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resistance. https://bit.ly/3i43wb6