Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting.
Milburn, James;
Lechiile, Kwana;
Siamisang, Keatlaretse;
Williams, Christopher G;
Owen, Leah;
Gwakuba, Ezekiel;
Machiya, Tichaona;
Leeme, Tshepo;
Barton, Hannah E;
Doyle, Ronan;
+5 more...Tenforde, Mark W;
Mine, Madisa;
Goldfarb, David M;
Mokomane, Margaret;
Jarvis, Joseph N;
(2022)
Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting.
Open forum infectious diseases, 9 (7).
ofac229-.
ISSN 2328-8957
DOI: https://doi.org/10.1093/ofid/ofac229
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The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) detection in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in patients with suspected meningoencephalitis in high human immunodeficiency virus-prevalence African settings are not known. We describe the clinical and laboratory characteristics of 13 patients with HHV-6 CSF PCR positivity in Botswana.