Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19.

Linzy Houchen-Wolloff ; Krisnah Poinasamy ; Kate Holmes ; Maryrose Tarpey ; Claire Hastie ; Kelly Raihani ; Natalie Rogers ; Nikki Smith ; Dawn Adams ; Paul Burgess ; +31 more... Jean Clark ; Clare Cranage ; Mahadev Desai ; Nicola Geary ; Rhyan Gill ; Jitendra Mangwani ; Lily Staunton ; Colin Berry ; Charlotte E Bolton

; Trudie Chalder ; James Chalmers ; Anthony De Soyza ; Omer Elneima

; John Geddes ; Simon Heller ; Ling-Pei Ho ; Joseph Jacob ; Hamish McAuley ; Aarti Parmar ; Jennifer K Quint

; Betty Raman ; Matthew Rowland ; Amisha Singapuri ; Sally J Singh ; David Thomas ; Mark R Toshner

; Louise V Wain ; Alex Robert Horsley

; Michael Marks

; Christopher E Brightling

; Rachael A Evans

; (2022) Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19. Thorax, 77 (7). pp. 717-720. ISSN 0040-6376 DOI: 10.1136/thoraxjnl-2021-218582

Copy

Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included: identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.