Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19.

Houchen-Wolloff, Linzy; Poinasamy, Krisnah; Holmes, Kate; Tarpey, Maryrose; Hastie, Claire; Raihani, Kelly; Rogers, Natalie; Smith, Nikki; Adams, Dawn; Burgess, Paul; +31 more...Clark, Jean; Cranage, Clare; Desai, Mahadev; Geary, Nicola; Gill, Rhyan; Mangwani, Jitendra; Staunton, Lily; Berry, Colin; Bolton, Charlotte E

; Chalder, Trudie; Chalmers, James; De Soyza, Anthony; Elneima, Omer

; Geddes, John; Heller, Simon; Ho, Ling-Pei; Jacob, Joseph; McAuley, Hamish; Parmar, Aarti; Quint, Jennifer K

; Raman, Betty; Rowland, Matthew; Singapuri, Amisha; Singh, Sally J; Thomas, David; Toshner, Mark R

; Wain, Louise V; Horsley, Alex Robert

; Marks, Michael

; Brightling, Christopher E

; and Evans, Rachael A

(2022) Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19. Thorax, 77 (7). pp. 717-720. ISSN 0040-6376 DOI: 10.1136/thoraxjnl-2021-218582

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Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included: identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.