This brief summarises lessons learned about the monitoring and evaluation (M&E) of COVID-19 prevention programmes. In this brief, we describe how M&E approaches have changed during the pandemic and outline 6 ways to strengthen future programmatic learning. The lessons shared in this brief are drawn from the work of the COVID-19 Hygiene Hub. This brief is primarily designed for people working within the water, sanitation and hygiene (WASH) sector and others who have been involved in COVID-19 prevention programming.