Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019.

Roberts, DJ; Davis, GS; Cole, MJ; Naik, D; Maru, H; Woodford, N; Muir, P; Horner, P; Simms, I; Thickett, G; +8 more...Crook, P; Foster, K; Andrews, N; Saunders, J; Fifer, H; Folkard, K; Gill, ON; incident management team and (2019) Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019. Eurosurveillance, 24 (38). pp. 2-6. ISSN 1560-7917 DOI: 10.2807/1560-7917.ES.2019.24.38.1900557
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We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%.
Item Type Article
Elements ID 159521
Date Deposited 30 Nov 2021 14:19

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