Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019.
David J
Roberts
;
Grahame S
Davis
;
Michelle J
Cole
;
Dixita
Naik
;
Hitiksha
Maru
;
Neil
Woodford
;
Peter
Muir
;
Paddy
Horner
;
Ian
Simms
;
George
Thickett
;
+8 more...
Paul
Crook
;
Kirsty
Foster
;
Nick
Andrews
;
John
Saunders
;
Helen
Fifer
;
Kate
Folkard
;
O Noel
Gill
;
incident management team
;
(2019)
Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019.
Eurosurveillance, 24 (38).
pp. 2-6.
ISSN 1560-7917
DOI: 10.2807/1560-7917.ES.2019.24.38.1900557
We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%.
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