Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil.
Stephanie LS
Penetra
;
Michele FB
da Silva
;
Paola
Resende
;
Anielle
Pina-Costa
;
Heloisa FP
Santos
;
Lusiele
Guaraldo
;
Guilherme A
Calvet
;
Maria
Ogrzewalska
;
Ighor
Arantes
;
Ketiuce
Zukeram
;
+17 more...
Mia F
de Araújo
;
Ana Beatriz Machado
Lima
;
Renata Serrano
Lopes
;
Larissa R
Lira-Silva
;
Isabella V
Moraes
;
Mayumi D
Wakimoto
;
Trevon L
Fuller
;
Claudia Raja
Gabaglia
;
Otávio M
Espíndola
;
Myrna C
Bonaldo
;
Cláudio Tadeu
Daniel-Ribeiro
;
Jimmy
Whitworth
;
Chris
Smith
;
Karin
Nielsen-Saines
;
Alex
Pauvolid-Correa
;
Marilda M
Siqueira
;
Patricia
Brasil
;
(2022)
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil.
International Journal of Infectious Diseases, 114.
pp. 58-61.
ISSN 1201-9712
DOI: 10.1016/j.ijid.2021.10.048
;
Chris
Smith
;
Karin
Nielsen-Saines
;
Alex
Pauvolid-Correa
;
Marilda M
Siqueira
;
Patricia
Brasil
;
(2022)
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil.
International Journal of Infectious Diseases, 114.
pp. 58-61.
ISSN 1201-9712
DOI: 10.1016/j.ijid.2021.10.048
We describe a case of prolonged COVID-19 caused by the SARS-CoV-2 Gamma variant in a fully vaccinated healthcare worker, 387 days after an infection caused by lineage B.1.1.33. Infections were confirmed by whole-genome sequencing and corroborated by the detection of neutralizing antibodies in convalescent serum samples. Considering the permanent exposure of this healthcare worker to SARS-CoV-2, the waning immunity after the first infection, the low efficacy of the inactivated vaccine at preventing COVID-19, the immune escape of the Gamma variant (VOC), and the burden of post-COVID syndrome, this individual would have benefited from an additional dose of a heterologous vaccine.
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picture_as_pdf - Penetra_etal_2021_Post-acute-covid-19-syndrome.pdf
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subject - Published Version
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- Available under Creative Commons: Attribution-NonCommercial-No Derivative Works 3.0
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