Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.

Adetifa, Ifedayo MO; Uyoga, Sophie; Gitonga, John N; Mugo, Daisy; Otiende, Mark; Nyagwange, James; Karanja, Henry K; Tuju, James; Wanjiku, Perpetual; Aman, Rashid; +25 more... Mwangangi, Mercy; Amoth, Patrick; Kasera, Kadondi; Ng'ang'a, Wangari; Rombo, Charles; Yegon, Christine; Kithi, Khamisi; Odhiambo, Elizabeth; Rotich, Thomas; Orgut, Irene; Kihara, Sammy; Bottomley, Christian; Kagucia, Eunice W; Gallagher, Katherine E; Etyang, Anthony; Voller, Shirine; Lambe, Teresa; Wright, Daniel; Barasa, Edwine; Tsofa, Benjamin; Bejon, Philip; Ochola-Oyier, Lynette I; Agweyu, Ambrose; Scott, J Anthony G; Warimwe, George M; (2021) Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya. Nature communications, 12 (1). 3966-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-021-24062-3

Abstract

Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.

Additional Information

Item Type	Article
Faculty and Department	Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Research Centre	Centre for Epidemic Preparedness and Response
PubMed ID	34172732
Elements ID	163088