Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.
Ifedayo MO
Adetifa
;
Sophie
Uyoga
;
John N
Gitonga
;
Daisy
Mugo
;
Mark
Otiende
;
James
Nyagwange
;
Henry K
Karanja
;
James
Tuju
;
Perpetual
Wanjiku
;
Rashid
Aman
;
+25 more...
Mercy
Mwangangi
;
Patrick
Amoth
;
Kadondi
Kasera
;
Wangari
Ng'ang'a
;
Charles
Rombo
;
Christine
Yegon
;
Khamisi
Kithi
;
Elizabeth
Odhiambo
;
Thomas
Rotich
;
Irene
Orgut
;
Sammy
Kihara
;
Christian
Bottomley
;
Eunice W
Kagucia
;
Katherine E
Gallagher
;
Anthony
Etyang
;
Shirine
Voller
;
Teresa
Lambe
;
Daniel
Wright
;
Edwine
Barasa
;
Benjamin
Tsofa
;
Philip
Bejon
;
Lynette I
Ochola-Oyier
;
Ambrose
Agweyu
;
J Anthony G
Scott
;
George M
Warimwe
;
(2021)
Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.
Nature communications, 12 (1).
3966-.
ISSN 2041-1723
DOI: 10.1038/s41467-021-24062-3
Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.
Item Type | Article |
---|---|
Elements ID | 163088 |
Date Deposited | 15 Jul 2021 09:11 |
ORCID: https://orcid.org/0000-0003-2556-9407
ORCID: https://orcid.org/0000-0003-1746-7873
ORCID: https://orcid.org/0000-0002-1389-1813
ORCID: https://orcid.org/0000-0002-5241-8412
ORCID: https://orcid.org/0000-0002-4481-8889
ORCID: https://orcid.org/0000-0002-5604-7647
ORCID: https://orcid.org/0000-0001-7382-8675
ORCID: https://orcid.org/0000-0001-7711-897X
ORCID: https://orcid.org/0000-0002-8114-1838
ORCID: https://orcid.org/0000-0001-8760-1279
ORCID: https://orcid.org/0000-0001-7533-5006
ORCID: https://orcid.org/0000-0002-4911-6333