Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity.

Franco, Caio H; Warhurst, David C; Bhattacharyya, Tapan; Au, Ho YA; Le, Hai; Giardini, Miriam A; Pascoalino, Bruno S; Torrecilhas, Ana Claudia; Romera, Lavinia MD; Madeira, Rafael Pedro; +5 more... Schenkman, Sergio; Freitas-Junior, Lucio H; Chatelain, Eric; Miles, Michael A; Moraes, Carolina B; (2020) Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, 13. pp. 107-120. ISSN 2211-3207 DOI: https://doi.org/10.1016/j.ijpddr.2020.06.001

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