Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.
Bojang, Abdoulie
; Baines, Sarah L; Camara, Bully; Guerillot, Romain; Donovan, Liam; Marqués, Raquel Sánchez; Secka, Ousman; D'Alessandro, Umberto; Bottomley, Christian; Howden, Benjamin P; and +1 more...Roca, Anna
(2020)
Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 (12).
pp. 3222-3225.
ISSN 1058-4838
DOI: 10.1093/cid/ciaa609
; Baines, Sarah L; Camara, Bully; Guerillot, Romain; Donovan, Liam; Marqués, Raquel Sánchez; Secka, Ousman; D'Alessandro, Umberto; Bottomley, Christian; Howden, Benjamin P; and +1 more...Roca, Anna
(2020)
Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 (12).
pp. 3222-3225.
ISSN 1058-4838
DOI: 10.1093/cid/ciaa609
UNLABELLED: In a post hoc analysis of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose mothers had been treated with the drug had higher prevalence of macrolide-resistance genes msr(A) and ermC at 28 days but not at 12 months. The 2 genes were positively associated in the nasopharynx. CLINICAL TRIALS REGISTRATION: NCT1800942.
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