Cytomegalovirus-Specific Immunoglobulin G is associated with chronic lung disease in children and adolescents from sub-Saharan Africa with perinatal HIV infection.
Hameiri Bowen, Dan;
Sovershaeva, Evgeniya;
Charlton, Bethany;
Schive, Cecilie;
Odland, Jon;
McHugh, Grace;
Bandason, Tsitsi;
Mayini, Justin;
Ferrand, Rashida A;
Yindom, Louis-Marie;
+1 more...Rowland-Jones, Sarah L;
(2020)
Cytomegalovirus-Specific Immunoglobulin G is associated with chronic lung disease in children and adolescents from sub-Saharan Africa with perinatal HIV infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
ISSN 1058-4838
DOI: https://doi.org/10.1093/cid/ciaa1757
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In a cross-sectional study of 296 perinatally HIV-infected children and adolescents from Zimbabwe, individuals with the top tertile of CMV-Specific Immunoglobulin G titre had an increased odds of chronic lung disease (odds ratio 3.33; 95% confidence interval 1.37-8.85; p = 0.010).