Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020.

Alma Tostmann ; John Bradley ORCID logo ; Teun Bousema ; Wing-Kee Yiek ; Minke Holwerda ; Chantal Bleeker-Rovers ; Jaap Ten Oever ; Corianne Meijer ; Janette Rahamat-Langendoen ; Joost Hopman ; +2 more... Nannet van der Geest-Blankert ; Heiman Wertheim ; (2020) Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 25 (16). pp. 2-7. ISSN 1025-496X DOI: 10.2807/1560-7917.ES.2020.25.16.2000508
Copy

Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.
Item Type Article
Elements ID 147162
Date Deposited 12 Jun 2020 09:34

Explore Further

picture_as_pdf
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers,.pdf
subject
Published Version
Available under Creative Commons: Attribution 3.0
View Download

Atom BibTeX OpenURL ContextObject in Span Multiline CSV OpenURL ContextObject Dublin Core Dublin Core MPEG-21 DIDL Data Cite XML EndNote HTML Citation JSON MARC (ASCII) MARC (ISO 2709) METS MODS RDF+N3 RDF+N-Triples RDF+XML RIOXX2 XML Reference Manager Refer Simple Metadata ASCII Citation EP3 XML
Export

Downloads