Introduction: Samvedana Plus is a multi-level intervention working with sex workers, their intimate partners (IP) and communities to reduce intimate partner violence (IPV) and increase condom use within intimate relationships of sex workers in Northern Karnataka, India. Methods: A cluster randomised control trial (cRCT) in 47 villages. Female sex workers with an IP in the last 6 months were eligible for baseline (2014), midline (2016) and endline (2017) surveys. 24 villages were randomised to Samvedana Plus and 23 to a wait-list control. Primary outcomes among sex workers included: experience of physical and/or sexual IPV or severe physical/sexual IPV in the last 6 months; consistent condom use with their IP in past 30 days. Analyses adjusted for clustering, and baseline cluster level means of outcomes. Result: Baseline (n=620) imbalance was observed in respect to age (33.9 vs. 35.2) and IPV (31.4% vs. 45.0%). No differences in physical/sexual IPV (8∙1% vs 9∙0%), severe physical/ IPV (6∙9% vs 8∙7%), or consistent condom use with IPs (62∙5% vs 57∙3%) were observed by trial arm at endline (n=547). Samvedana Plus was associated with decreased acceptance of IPV (AOR=0∙62, 95% CI 0∙40-0∙94, p=0∙025), increased awareness of self-protection strategies (AOR=1∙73, 95% CI=1∙04-2∙89, p=0.035), and solidarity of sex workers around issues of IPV (AOR=1∙69, 95% CI=1∙02-2∙82, p=0∙042). We observed an increase in IPV between baseline (25∙9%) and midline (63∙5%) among women in Samvedana Plus villages but lower in comparison villages (41∙8% to 44∙3%) and a sharp decrease at endline in both arms (~7%). Conclusion: We found no evidence that Samvedana Plus reduced IPV or increased condom use, but itmay impact acceptance of IPV, increase knowledge of self-protection strategies and increase sex worker solidarity. Inconsistencies in reported IPV undermined the ability of the trial to assess effectiveness. Trial registration: NCT02807259