Mayaud, P; Grosskurth, H; Changalucha, J; Todd, J; West, B; Gabone, R; Senkoro, K; Rusizoka, M; Laga, M; Hayes, R; +1 more... Mabey, D; (1995) Risk assessment and other screening options for gonorrhoea and chlamydial infections in women attending rural Tanzanian antenatal clinics. BULLETIN OF THE WORLD HEALTH ORGANIZATION, 73 (5). pp. 621-630. ISSN 0042-9686 https://researchonline.lshtm.ac.uk/id/eprint/4654008
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https://researchonline.lshtm.ac.uk/id/eprint/4654008
Abstract
Sexually transmitted diseases (STDs) are a major cause of morbidity and mortality in developing countries and may play a key role in enhancing the heterosexual transmission of human immunodeficiency virus (HIV). Treatment of STDs is one of the most cost-effective of all health interventions in developing countries; however, STDs among women in rural populations have received little attention. In this study, we report that prevalences of STDs among 964 women attending antenatal clinics in a rural area of the United Republic of Tanzania. A total of 378 (39%) of these women were infected with at least one STD pathogen, 97 (10%) had syphilis, and 81 (8%) has Neisseria gonorrhoeae (NG) and/or Chlamydia trachomatis (CT) infection. The recommended syndromic approach to screening for NG/CT infection, based on reported genital symptoms, had a low sensitivity (43%) and failed to discriminate between infected and uninfected women. A risk score approach that we developed, based on sociodemographic and other factors associated with NG/CT infection, had a higher sensitivity and lower cost per true case treated than other approaches, although its positive predictive value was only about 20%.
Item Type | Article |
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Faculty and Department |
Faculty of Infectious and Tropical Diseases > Dept of Clinical Research Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) |
PubMed ID | 8846488 |
Elements ID | 110121 |