Relapse-free cure from multidrug-resistant tuberculosis in Germany.

Jan Heyckendorf ORCID logo ; Frank van Leth ; Barbara Kalsdorf ; Ioana D Olaru ORCID logo ; Gunar Günther ; Helmut JF Salzer ; Elena Terhalle ; Thierry Rolling ; Georg Glattki ; Marius Müller ; +3 more... Maren Schuhmann ; Korkut Avsar ; Christoph Lange ; (2018) Relapse-free cure from multidrug-resistant tuberculosis in Germany. The European respiratory journal, 51 (2). p. 1702122. ISSN 0903-1936 DOI: 10.1183/13993003.02122-2017
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Multidrug-resistant (MDR) tuberculosis (TB), defined by bacillary resistance against rifampicin and isoniazid, has been identified as a global threat to mankind [1]. According to the latest report by the European Centres for Disease Prevention and Control, and World Health Organization (WHO) regional office for Europe, only approximately 50% of MDR-TB patients in Europe reach favourable treatment outcomes [2]. Successful treatment outcomes are achieved for less than 25% of patients with extensively drug-resistant (XDR)-TB (MDR plus resistance against a least one fluoroquinolone and one second-line injectable drug) in the European Union/European Economic Area Countries [2].


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