Full Genomic Characterization of a Saffold Virus Isolated in Peru.

Leguia, Mariana; Loyola, Steev; Rios, Jane; Juarez, Diana; Guevara, Carolina; Silva, Maria; Prieto, Karla; Wiley, Michael; Kasper, Matthew R; Palacios, Gustavo; +1 more... Bausch, Daniel G; (2015) Full Genomic Characterization of a Saffold Virus Isolated in Peru. PATHOGENS, 4 (4). pp. 816-825. ISSN 2076-0817 DOI: https://doi.org/10.3390/pathogens4040816

Abstract

While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.