Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection Among Women Living With Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study.

Jason J Ong ; Mahlape Precious Magooa ; Admire Chikandiwa ; Helen Kelly ; Marie-Noelle Didelot ; Etienne E Muller ; Venessa Maseko ; Michel Segondy ; Sinead Delany-Moretlwe ; Ranmini Kularatne ; +2 more... Philippe Mayaud ORCID logo ; HIV in Africa Research Partnership Study Group ; (2019) Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection Among Women Living With Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study. Clinical Infectious Diseases, 69 (5). pp. 873-876. ISSN 1058-4838 DOI: 10.1093/cid/ciz045
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This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4% (95% confidence interval [CI]: 5.5-9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL decrease, 95% CI: 1.00-1.03) and higher plasma HIV-1 RNA (AOR 1.15 per log copies/mL increase, 95% CI: 1.03-1.27). No mutations for macrolide/quinolone resistance was detected.


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