Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel.

Adi Behar ; Kate Susan Baker ; Ravit Bassal ; Analia Ezernitchi ; Lea Valinsky ; Nicholas R Thomson ORCID logo ; Daniel Cohen ; (2018) Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel. EMERGING INFECTIOUS DISEASES, 24 (7). pp. 1335-1339. ISSN 1080-6040 DOI: 10.3201/eid2407.171313
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Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000-2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes, and little genetic variation within the O antigen: highly relevant for Shigella vaccine development.
Item Type Article
Date Deposited 15 Jan 2019 13:13

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