Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C virus infection.
Cresswell, Fiona V;
Fisher, Martin;
Hughes, Daniel J;
Shaw, Simon G;
Homer, Gary;
Hassan-Ibrahim, Mohammed O;
(2014)
Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C virus infection.
Clinical infectious diseases, 60 (2).
pp. 263-266.
ISSN 1058-4838
DOI: https://doi.org/10.1093/cid/ciu782
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Hepatitis C virus (HCV) is increasingly common among human immunodeficiency virus (HIV)-infected men who have sex with men. We evaluated the efficacy of HCV core antigen in diagnosing acute HCV in an HIV-infected cohort. Compared with HCV polymerase chain reaction, core antigen proved sensitive (100%) and specific (97.9%). As a quick, simple, and cost-effective test, it has considerable utility in screening for acute HCV.