The mycobacterium-specific gene Rv2719c is DNA damage inducible independently of RecA.
Brooks, Patricia C;
Dawson, Lisa F;
Rand, Lucinda;
Davis, Elaine O;
(2006)
The mycobacterium-specific gene Rv2719c is DNA damage inducible independently of RecA.
Journal of bacteriology, 188 (16).
pp. 6034-6038.
ISSN 0021-9193
DOI: https://doi.org/10.1128/JB.00340-06
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The mycobacterium-specific gene Rv2719c was found to be expressed primarily from a promoter that was clearly DNA damage inducible independently of RecA. Upstream of the transcriptional start site for this promoter, sequence motifs resembling those observed previously at the RecA-independent, DNA damage-inducible recA promoter were identified, and the -10 motif was demonstrated by mutational analysis in transcriptional fusion constructs to be important for expression of Rv2719c.