Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test.

Reithinger, R; Grijalva, MJ; Chiriboga, RF; de Noya, BA; Torres, JR; Pavia-Ruz, N; Manrique-Saide, P; Cardinal, MV; Gürtler, RE and (2010) Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test. Journal of clinical microbiology, 48 (8). pp. 3003-3007. ISSN 0095-1137 DOI: 10.1128/JCM.02474-09
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We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known serological results from Argentina, Ecuador, Mexico, and Venezuela. One hundred forty-nine of 366 (40.7%) and 171/366 (46.7%) samples tested positive by dipstick and serology, respectively. Dipstick sensitivity was calculated to be 84.8% (range between countries, 77.5 to 95%), and specificity was 97.9% (95.9 to 100%).

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