Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.

Ramakrishnan, G; Wright, M; Alam, M; Naylor, C; Kabir, M; Zerin, A; Ferdous, T; Pedersen, K; Hennig, B; Donowitz, J; +5 more...Wegmuller, R; Haque, R; Petri, W; Herbein, J; Gilchrist, C and (2016) Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia. Diagnostic microbiology and infectious disease. ISSN 0732-8893 DOI: 10.1016/j.diagmicrobio.2016.11.011
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We have developed recombinant fragment C based rapid point of care dipstick devices to assess tetanus immunization status using plasma or whole blood. The devices demonstrated specificity of 0.90 and sensitivity of 0.90 (whole blood)/0.94 (plasma) at field sites in Bangladesh and The Gambia when compared to a commercial ELISA with the immune cut-off titer set as ≥0.1IU/mL.
Item Type Article
ISI 394407700017
Date Deposited 17 Dec 2016 02:17

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