Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa.

Monde Muyoyeta ; Petra EW de Haas ; Dirk H Mueller ; Paul D van Helden ; Lawrence Mwenge ; Ab Schaap ; Clarissa Kruger ; Nicolaas C Gey van Pittius ; Katherine Lawrence ; Nulda Beyers ; +2 more... Peter Godfrey-Faussett ORCID logo ; Helen Ayles ORCID logo ; (2010) Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa. Journal of clinical microbiology, 48 (10). pp. 3773-3775. ISSN 0095-1137 DOI: 10.1128/JCM.01688-09
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The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings.

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