Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
O'Neill, PM; Amewu, RK; Nixon, GL; Bousejra ElGarah, F; Mungthin, M; Chadwick, J; Shone, AE; Vivas, L; Lander, H; Barton, V; +9 more...Muangnoicharoen, S; Bray, PG; Davies, J; Park, BK; Wittlin, S; Brun, R; Preschel, M; Zhang, K; Ward, SA and
(2010)
Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
Angewandte Chemie (International ed in English), 49 (33).
pp. 5693-5697.
ISSN 1433-7851
DOI: 10.1002/anie.201001026
| Item Type | Article |
|---|---|
| Keywords | antimalarial agents, drug development, endoperoxides, medicinal, chemistry, tetraoxanes, MALARIA TREATMENT, RESISTANCE, STABILITY |
| ISI | 280891000015 |
| Date Deposited | 17 Oct 2011 14:10 |