Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom.

Hill, N; Moor, G; Cameron, MM; Butlin, A; Preston, S; Williamson, MS; Bass, C; (2005) Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom. BMJ, 331 (7513). pp. 384-387. ISSN 0959-8146 DOI: https://doi.org/10.1136/bmj.38537.468623.E0

Abstract

OBJECTIVE: To compare the effectiveness of the Bug Buster kit with a single treatment of over the counter pediculicides for eliminating head lice. DESIGN: Single blind, multicentre, randomised, comparative clinical study. SETTING: Four counties in England and one county in Scotland. PARTICIPANTS: 133 young people aged 2-15 years with head louse infestation: 56 were allocated to the Bug Buster kit and 70 to pediculicide treatment. INTERVENTIONS: Home use of proprietary pediculicides (organophosphate or pyrethroid) or the Bug Buster kit. MAIN OUTCOME MEASURE: Presence of head lice 2-4 days after end of treatment: day 5 for the pediculicides and day 15 for the Bug Buster kit. RESULTS: The cure rate using the Bug Buster kit was significantly greater than that for the pediculicides (57% v 13%; relative risk 4.4, 95% confidence interval 2.3 to 8.5). Number needed to treat for the Bug Buster kit compared with the pediculicides was 2.26. CONCLUSION: The Bug Buster kit was the most effective over the counter treatment for head louse infestation in the community when compared with pediculicides.

Additional Information

Item Type	Article
Keywords	Resistance, permethrin, malathion, trial
Faculty and Department	Faculty of Infectious and Tropical Diseases > Dept of Disease Control
ISI	231319900016