Marks, Michael; Mitjà, Oriol; Solomon, Anthony W; Asiedu, Kingsley B; Mabey, David C; (2014) Yaws. British medical bulletin, 113 (1). pp. 91-100. ISSN 0007-1420 DOI: https://doi.org/10.1093/bmb/ldu037
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Abstract
INTRODUCTION: Yaws, caused by Treponema pallidum ssp. pertenue, is endemic in parts of West Africa, Southeast Asia and the Pacific. The WHO has launched a campaign based on mass treatment with azithromycin, to eradicate yaws by 2020. SOURCES OF DATA: We reviewed published data, surveillance data and data presented at yaws eradication meetings. AREAS OF AGREEMENT: Azithromycin is now the preferred agent for treating yaws. Point-of-care tests have demonstrated their value in yaws. AREAS OF CONTROVERSY: There is limited data from 76 countries, which previously reported yaws. Different doses of azithromycin are used in community mass treatment for yaws and trachoma. GROWING POINTS: Yaws eradication appears an achievable goal. The programme will require considerable support from partners across health and development sectors. AREAS TIMELY FOR DEVELOPING RESEARCH: Studies to complete baseline mapping, integrate diagnostic tests into surveillance and assess the impact of community mass treatment with azithromycin are ongoing.
Item Type | Article |
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Faculty and Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
Research Centre | Neglected Tropical Diseases Network |
PubMed ID | 25525120 |
ISI | 351512300009 |
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Filename: Yaws_BMB_2014_11_07.docx
Licence: Creative Commons: Attribution-Noncommercial-No Derivative Works 3.0
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