A simplified cost-effectiveness model to guide decision-making for shortened anti-tuberculosis treatment regimens.
Zwerling, A;
Gomez, GB;
Pennington, J;
Cobelens, F;
Vassall, A;
Dowdy, DW;
(2016)
A simplified cost-effectiveness model to guide decision-making for shortened anti-tuberculosis treatment regimens.
The international journal of tuberculosis and lung disease, 20 (2).
pp. 257-260.
ISSN 1027-3719
DOI: https://doi.org/10.5588/ijtld.15.0415
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User-friendly models (UFMs) allow local decision makers to explore relationships and apply results from more detailed models of such outcomes as cost-effectiveness. When developing UFMs, modelers must decide which simplifications may be appropriate, enabling the UFM to retain accuracy while reducing complexity. We use the example of cost-effectiveness analysis (CEA) for novel shortened anti-tuberculosis treatment regimens across four settings to demonstrate how UFMs can allow decision makers to adapt published results to their local context. We simplified a complex model to produce a UFM that provides similar results, the ability to modify key parameter values, and receive customized results in seconds.