Impact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials.
Mehran, Roxana;
Pocock, Stuart;
Nikolsky, Eugenia;
Dangas, George D;
Clayton, Tim;
Claessen, Bimmer E;
Caixeta, Adriano;
Feit, Frederick;
Manoukian, Steven V;
White, Harvey;
+6 more...Bertrand, Michel;
Ohman, E Magnus;
Parise, Helen;
Lansky, Alexandra J;
Lincoff, A Michael;
Stone, Gregg W;
(2011)
Impact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials.
JACC. Cardiovascular interventions, 4 (6).
pp. 654-64.
ISSN 1876-7605
https://researchonline.lshtm.ac.uk/id/eprint/20523
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Non-CABG-related bleeding within 30 days is strongly associated with an increased risk of subsequent mortality at 1 year in patients undergoing PCI for all indications. A risk score was established to calculate the bleeding risk for patients undergoing PCI, allowing therapeutic decision making to minimize the incidence of bleeding.
