Asymmetric PPCys: strongly fluorescing NIR labels.

Georg Michael Fischer ; Christian Jüngst ; Magnus Isomäki-Krondahl ; Dominik Gauss ; Heiko Michael Möller ; Ewald Daltrozzo ; Andreas Zumbusch ; (2010) Asymmetric PPCys: strongly fluorescing NIR labels. Chemical communications (Cambridge, England), 46 (29). pp. 5289-5291. ISSN 1364-548X DOI: 10.1039/c0cc00359j

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By a stepwise synthesis strategy biofunctionalized Pyrrolopyrrole Cyanines (PPCy) with an asymmetric substitution pattern were obtained. These exhibit extremely strong and narrowband NIR absorption and fluorescence. Internalization of a peptide bound PPCy is demonstrated using live cell microscopy.

Item Type	Article
Date Deposited	03 Dec 2011 02:48

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