Added value of an oropharyngeal swab in detection of viruses in children hospitalized with lower respiratory tract infection.
Hammitt, Laura L;
Kazungu, Sidi;
Welch, Steve;
Bett, Anne;
Onyango, Clayton O;
Gunson, Rory N;
Scott, J Anthony G;
Nokes, D James;
(2011)
Added value of an oropharyngeal swab in detection of viruses in children hospitalized with lower respiratory tract infection.
Journal of clinical microbiology, 49 (6).
pp. 2318-2320.
ISSN 0095-1137
DOI: https://doi.org/10.1128/JCM.02605-10
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Paired nasopharyngeal and oropharyngeal swabs collected from 533 children hospitalized with lower respiratory tract infection were assessed by multiplex reverse transcription-PCR. Oropharyngeal swabs increased the number of viral infections detected by 15%, compared to collection of a nasopharyngeal swab alone. This advantage was most pronounced for detection of influenza, parainfluenza, and adenovirus.