Plasmid copy number and disease severity in naturally occurring ocular Chlamydia trachomatis infection.

Anna R Last ORCID logo ; Chrissy H Roberts ORCID logo ; Eunice Cassama ; Meno Nabicassa ; Sandra Molina-Gonzalez ; Sarah E Burr ; David CW Mabey ORCID logo ; Robin L Bailey ORCID logo ; Martin J Holland ORCID logo ; (2013) Plasmid copy number and disease severity in naturally occurring ocular Chlamydia trachomatis infection. Journal of clinical microbiology, 52 (1). pp. 324-327. ISSN 0095-1137 DOI: 10.1128/JCM.02618-13
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The Chlamydia trachomatis plasmid is a virulence factor. Plasmid copy number, C. trachomatis load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]) and there were no associations with C. trachomatis load or disease severity.
Item Type Article
ISI 329222400051
Date Deposited 08 Nov 2013 20:57

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