Comparison of CareHPV and Hybrid Capture 2 Assays for Detection of High-Risk HPV DNA in Cervical Samples from HIV-1-Infected African Women.

Ngou, J; Magooa, MP; Gilham, C; Djigma, F; Didelot, MN; Kelly, H; Yonli, A; Sawadogo, B; Lewis, DA; Delany-Moretlwe, S; +3 more... Mayaud, P; Segondy, M; HARP Study Group; (2013) Comparison of CareHPV and Hybrid Capture 2 Assays for Detection of High-Risk HPV DNA in Cervical Samples from HIV-1-Infected African Women. Journal of clinical microbiology, 51 (12). pp. 4240-2. ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.02144-13

Abstract

: The careHPV and HC2 assays were compared for high-risk human papillomavirus (HR-HPV) DNA detection in cervical samples from 149 HIV-1-infected African women. The HR-HPV DNA detection rates were 37.6% and 34.9% for careHPV and HC2, respectively. Agreement between the two tests was 94.6% (95% confidence interval [CI], 89.7% to 97.7%) with a kappa value of 0.88 (95% CI, 0.81 to 0.96), indicating an excellent agreement. careHPV may be considered as suitable as HC2 for cervical cancer screening among HIV-infected African women.<br/>

Additional Information

Item Type	Article
Faculty and Department	Faculty of Infectious and Tropical Diseases > Dept of Clinical Research Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Research Centre	Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID	24108613
ISI	327147100062
Related URLs	OA Location