Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection.
Ana
Cehovin
;
Jacqueline M
Cliff
;
Philip C
Hill
;
Roger H
Brookes
;
Hazel M
Dockrell
;
(2007)
Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection.
Clinical and vaccine immunology, 14 (6).
pp. 796-798.
ISSN 1556-6811
DOI: 10.1128/CVI.00093-07
To test the hypothesis that prolonged culture would enhance the sensitivity of latent tuberculosis detection by a gamma interferon release assay, blood samples from 33 household contacts of Gambian tuberculosis patients were stimulated with Mycobacterium tuberculosis-specific antigens. After 24 h of culture, 66% were positive, compared to 93% after 6 days of culture.
Item Type | Article |
---|---|
ISI | 247769500024 |
Date Deposited | 17 Oct 2011 17:57 |
Explore Further
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951098 (OA Location)
- 10.1128/CVI.00093-07 (DOI)
- 17460111 (PubMed)
ORCID: https://orcid.org/0000-0002-5653-1818
ORCID: https://orcid.org/0000-0003-1869-9107