Frequency of CCR5 variants among rural populations with low HIV-1 prevalence in Cameroon.
Judith N
Torimiro
;
Nathan D
Wolfe
;
Alero
Thomas
;
Maureen P
Martin
;
Eitel
Mpoudi-Ngole
;
Ubald
Tamoufe
;
Deborah L
Birx
;
Mary
Carrington
;
Donald S
Burke
;
Jean K
Carr
;
(2007)
Frequency of CCR5 variants among rural populations with low HIV-1 prevalence in Cameroon.
AIDS (London, England), 21 (4).
pp. 527-528.
ISSN 0269-9370
DOI: 10.1097/QAD.0b013e328045c4bd
Among rural populations in Cameroon, HIV-1 prevalence is low and the genetic diversity broad. An unusual population-level genetic background may modulate this pattern of HIV infection. We examined HIV-1 prevalence, CCR5Delta32 and CCR5 promoter -2459 G genotype frequency among 1390 rural inhabitants. No individual was identified with the CCR5Delta32 allele, but homozygotes for the CCR5 promoter variant -2459G (27.5%) were relatively common. A seroprevalence of 3.1% of HIV-1 was reported.
| Item Type | Article |
|---|---|
| ISI | 244910000019 |
| Date Deposited | 17 Oct 2011 17:55 |