Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial.
Jarvis, Joseph N;
Chou, Roger;
Harrison, Thomas S;
Lawrence, David S;
Muthoga, Charles;
Mupeli, Kennedy;
Meya, David B;
Mwandumba, Henry C;
Kanyama, Cecilia;
Meintjes, Graeme;
+7 more...Leeme, Tshepo B;
Ndhlovu, Chiratidzo E;
Beattie, Pauline;
Sued, Omar;
Pérez Casas, Carmen;
Makanga, Michael;
Ford, Nathan;
(2023)
Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial.
The Lancet Global health, 11 (11).
e1688-e1690.
ISSN 2214-109X
DOI: https://doi.org/10.1016/S2214-109X(23)00412-6
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Translating evidence from clinical trials to routine
care can take many years, particularly in low-income
and middle-income countries, delaying access to lifesaving or life-changing treatments. As few as one in five
evidence-based health interventions are incorporated
into routine use, and the average time lag between
evidence availability and practice change is up to
17 years.