The data presented in this article were used to estimate the impacts of air pollution policies on population health and health inequalities within a spatial microsimulation model, MicroEnv [1]. They provide a basis for comparison with similar models and allow researchers to integrate additional model components without duplication of effort. Relative risk estimates for the association between air pollution and rates of ischaemic heart disease (IHD) incidence, IHD case fatality and all-cause mortality were taken from a review of the epidemiological literature and meta-analyses [2]. Modelled small area air pollution data (PM2.5) for Greater London, UK were obtained from an environmental consultancy. All other data were collected from open source Governmental or Non-Government Organisation (NGO) data repositories. These include all-cause mortality rates; IHD incidence, prevalence and mortality rates; general fertility rates; small area socio-economic deprivation data; and relative risk estimates for the association between deprivation and all-cause mortality.