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Anya Burton, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martín Lajous, Ruy López-Ridaura, Megan Rice, Ana Pereira, Maria Luisa Garmendia, Rulla M. Tamimi, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Samera A. Qureshi, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, Rose Ndumia, Sudhir Vinayak, Soo-Hwang Teo, Shivaani Mariapun, Farhana Fadzli, Beata Peplonska, Agnieszka Bukowska, Chisato Nagata, Jennifer Stone, John Hopper, Graham Giles, Vahit Ozmen, Mustafa Erkin Aribal, Joachim Schüz, Carla H. Van Gils, Johanna O. P. Wanders, Reza Sirous, Mehri Sirous, John Hipwell, Jisun Kim, Jong Won Lee, Caroline Dickens, Mikael Hartman, Kee-Seng Chia, Christopher Scott, Anna M. Chiarelli, Linda Linton, Marina Pollan, Anath Arzee Flugelman, Dorria Salem, Rasha Kamal, Norman Boyd, Isabel dos-Santos-Silva, Valerie McCormack
Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide
www.plosmedicine.org
www.plosmedicine.org
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(=)Tj
0.7994 0 Td
(3\),)Tj
1.2586 0 Td
(or)Tj
1.0998 0 Td
(a)Tj
0.652 0 Td
(combination)Tj
5.3518 0 Td
(of)Tj
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1.7631 0 Td
(menstruation,)Tj
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2.5171 0 Td
(replacement)Tj
5.1477 0 Td
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3.2485 0 Td
(\(HRT\),)Tj
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(and)Tj
1.7348 0 Td
(hysterectomy/oophorectomy)Tj
11.7751 0 Td
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3.0047 0 Td
(\()Tj
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[()]TJ
/F6 1 Tf
1.0885 0 Td
(=)Tj
0.7993 0 Td
(2\).)Tj
1.2643 0 Td
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-33.7037 -1.2983 Td
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3.2484 0 Td
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3.1975 0 Td
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2.126 0 Td
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(10)Tj
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3.719 0 Td
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5.709 0 Td
(an)Tj
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(2.8)Tj
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6.616 0 Td
(a)Tj
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(premenopausal)Tj
6.3496 0 Td
(woman)Tj
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(at)Tj
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(the)Tj
1.4683 0 Td
(time)Tj
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(of)Tj
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(the)Tj
1.4683 0 Td
(questionnaire)Tj
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(postmenopausal)Tj
6.7181 0 Td
(at)Tj
0.9524 0 Td
(the)Tj
1.4683 0 Td
(time)Tj
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(of)Tj
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(mammography)Tj
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(if)Tj
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(her)Tj
1.542 0 Td
(age)Tj
1.542 0 Td
(at)Tj
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(mammography)Tj
6.3892 0 Td
(exceeded)Tj
3.8608 0 Td
(the)Tj
1.4683 0 Td
(study's)Tj
2.965 0 Td
(mean)Tj
2.4435 0 Td
(age)Tj
1.542 0 Td
(at)Tj
0.9525 0 Td
(menopause.)Tj
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3.0784 0 Td
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1.9729 0 Td
(centrally)Tj
3.668 0 Td
(in)Tj
1.0375 0 Td
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3.8948 0 Td
([)Tj
0.83 0.64 0.02 0 k
(19)Tj
0 g
(])Tj
1.8481 0 Td
(on)Tj
1.2756 0 Td
(digitised)Tj
3.6227 0 Td
(film-screen,)Tj
4.9719 0 Td
(raw)Tj
1.7065 0 Td
(digital,)Tj
2.9536 0 Td
(or)Tj
-35.8863 -1.2983 Td
(processed)Tj
4.1328 0 Td
(digital)Tj
2.7269 0 Td
(images,)Tj
3.2145 0 Td
(by)Tj
1.1849 0 Td
(1)Tj
0.6916 0 Td
(of)Tj
1.0148 0 Td
(3)Tj
0.6974 0 Td
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5.0343 0 Td
(readers)Tj
3.1351 0 Td
(\(VM,)Tj
2.3697 0 Td
(IdSS,)Tj
2.2677 0 Td
(NB\).)Tj
2.0976 0 Td
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1.6271 0 Td
(each)Tj
2.0296 0 Td
(woman,)Tj
3.4412 0 Td
(1)Tj
-35.6652 -1.3039 Td
(image)Tj
2.6305 0 Td
(\(craniocaudal)Tj
5.7033 0 Td
(or)Tj
1.0998 0 Td
(mediolateral)Tj
5.2157 0 Td
(oblique)Tj
3.2031 0 Td
(view\))Tj
2.3925 0 Td
(was)Tj
1.7007 0 Td
(read.)Tj
2.1997 0 Td
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3.0614 0 Td
(were)Tj
2.126 0 Td
(randomly)Tj
4.1272 0 Td
(allocated)Tj
-33.4599 -1.2983 Td
(to)Tj
1.0204 0 Td
(batches,)Tj
3.4186 0 Td
(and)Tj
1.7291 0 Td
(batches)Tj
3.1975 0 Td
(were)Tj
2.1203 0 Td
(randomly)Tj
4.1272 0 Td
(allocated)Tj
3.7587 0 Td
(to)Tj
1.0205 0 Td
(readers,)Tj
3.3562 0 Td
(as)Tj
1.0148 0 Td
(previously)Tj
4.3483 0 Td
(described)Tj
4.0535 0 Td
([)Tj
0.83 0.64 0.02 0 k
(16)Tj
0 g
(].)Tj
2.0749 0 Td
(Read-)Tj
-35.24 -1.2982 Td
(ings)Tj
1.8595 0 Td
(included)Tj
3.7133 0 Td
(3%)Tj
1.4514 0 Td
(within-reader,)Tj
5.9413 0 Td
(within-batch)Tj
5.3518 0 Td
(repeats)Tj
3.0501 0 Td
(and)Tj
1.7291 0 Td
(5%)Tj
1.457 0 Td
(between-reader)Tj
6.4289 0 Td
(repeats.)Tj
3.2712 0 Td
(MD)Tj
-34.2536 -1.2983 Td
(measures)Tj
3.9401 0 Td
(obtained)Tj
3.7304 0 Td
(were)Tj
2.1259 0 Td
(dense)Tj
2.5058 0 Td
(area,)Tj
2.1033 0 Td
(non-dense)Tj
4.4617 0 Td
(area,)Tj
2.109 0 Td
(and)Tj
1.7291 0 Td
(breast)Tj
2.6135 0 Td
(area)Tj
1.8822 0 Td
(\(dense)Tj
2.846 0 Td
(area)Tj
1.8822 0 Td
(+)Tj
0.7994 0 Td
(non-dense)Tj
-32.7286 -1.3039 Td
(area\),)Tj
2.4491 0 Td
(all)Tj
1.1452 0 Td
(in)Tj
1.0374 0 Td
(square)Tj
2.8403 0 Td
(centimetres,)Tj
5.1024 0 Td
(and)Tj
1.7348 0 Td
(PD)Tj
1.5136 0 Td
(\(PD)Tj
1.8539 0 Td
(=)Tj
0.7994 0 Td
(100)Tj
/F15 1 Tf
1.6497 0 Td
[()]TJ
/F6 1 Tf
0.788 0 Td
(dense)Tj
2.5058 0 Td
(area/breast)Tj
4.6035 0 Td
(area\).)Tj
2.4491 0 Td
(PD)Tj
1.5194 0 Td
(and)Tj
1.7291 0 Td
(dense)Tj
-33.7207 -1.2983 Td
(and)Tj
1.7291 0 Td
(non-dense)Tj
4.456 0 Td
(areas)Tj
2.245 0 Td
(that)Tj
1.7802 0 Td
(were)Tj
2.1203 0 Td
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1.9786 0 Td
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1.2755 0 Td
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4.1329 0 Td
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2.9934 0 Td
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2.1203 0 Td
(first)Tj
1.8085 0 Td
(corrected)Tj
3.9911 0 Td
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1.0205 0 Td
(a)Tj
0.6576 0 Td
(raw-image)Tj
-32.309 -1.2983 Td
(equivalent)Tj
4.3483 0 Td
(using)Tj
2.3924 0 Td
(published)Tj
4.1215 0 Td
(equations)Tj
4.0932 0 Td
([)Tj
0.83 0.64 0.02 0 k
(20)Tj
0 g
(].)Tj
-13.7592 -1.3039 Td
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2.2903 0 Td
(excluding)Tj
4.1103 0 Td
(poor-quality)Tj
5.21 0 Td
(images)Tj
2.9877 0 Td
(and)Tj
1.7348 0 Td
(suspected)Tj
4.0819 0 Td
(tumours)Tj
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(\()Tj
/F13 1 Tf
[()]TJ
/F6 1 Tf
1.0885 0 Td
(=)Tj
0.7994 0 Td
(288\),)Tj
2.211 0 Td
(women)Tj
3.2031 0 Td
(with)Tj
1.9956 0 Td
(no)Tj
-34.5427 -1.2982 Td
(BMI)Tj
2.0295 0 Td
(data)Tj
1.9163 0 Td
(\()Tj
/F13 1 Tf
[()]TJ
/F6 1 Tf
1.0884 0 Td
(=)Tj
0.7994 0 Td
(2\))Tj
1.0375 0 Td
(or)Tj
1.0942 0 Td
(with)Tj
2.0012 0 Td
(extreme)Tj
3.4412 0 Td
(BMIs)Tj
2.3925 0 Td
(\()Tj
/F14 1 Tf
0 Tc
(>)Tj
/F6 1 Tf
-0.004 Tc
(3.8)Tj
2.5114 0 Td
(SD)Tj
1.4287 0 Td
(from)Tj
2.211 0 Td
(her)Tj
1.542 0 Td
(population)Tj
4.5865 0 Td
(group)Tj
2.6078 0 Td
(mean,)Tj
/F13 1 Tf
2.6759 0 Td
[()]TJ
/F6 1 Tf
0.7484 0 Td
(=)Tj
0.7993 0 Td
(42\),)Tj
-34.9112 -1.2983 Td
(11,423)Tj
2.8232 0 Td
(women)Tj
3.2032 0 Td
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(included,)Tj
3.9401 0 Td
(11,232)Tj
2.8233 0 Td
(of)Tj
1.0148 0 Td
(whom)Tj
2.7552 0 Td
(had)Tj
1.7122 0 Td
(PD)Tj
1.5137 0 Td
(data,)Tj
2.1373 0 Td
(11,375)Tj
2.8233 0 Td
(dense-area)Tj
4.5183 0 Td
(readings,)Tj
3.8438 0 Td
(and)Tj
-35.2287 -1.3039 Td
(11,184)Tj
2.8232 0 Td
(non-dense-area)Tj
6.4687 0 Td
(and)Tj
1.7348 0 Td
(breast-area)Tj
4.6261 0 Td
(readings.)Tj
3.8437 0 Td
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(in)Tj
1.0375 0 Td
(the)Tj
1.4683 0 Td
(numbers)Tj
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(of)Tj
1.0148 0 Td
(women)Tj
3.1975 0 Td
(with)Tj
-34.7695 -1.2983 Td
(different)Tj
3.6566 0 Td
(MD)Tj
1.8482 0 Td
(metrics)Tj
3.1861 0 Td
(arose)Tj
2.3131 0 Td
(because,)Tj
3.5433 0 Td
(in)Tj
1.0374 0 Td
(some)Tj
2.3301 0 Td
(mammograms,)Tj
6.2985 0 Td
(dense)Tj
2.5059 0 Td
(area)Tj
1.8821 0 Td
(could)Tj
2.4492 0 Td
(be)Tj
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(estimated)Tj
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(but)Tj
1.5533 0 Td
(the)Tj
1.4684 0 Td
(breast)Tj
2.6135 0 Td
(edge)Tj
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(was)Tj
1.6951 0 Td
(not)Tj
1.5761 0 Td
(visible)Tj
2.7439 0 Td
(\(thus)Tj
2.279 0 Td
(PD,)Tj
1.7405 0 Td
(non-dense)Tj
4.456 0 Td
(area,)Tj
2.109 0 Td
(and)Tj
1.7291 0 Td
(breast)Tj
2.6135 0 Td
(area)Tj
1.8822 0 Td
(were)Tj
2.126 0 Td
(missing\),)Tj
-32.6492 -1.2982 Td
(and,)Tj
1.9558 0 Td
(for)Tj
1.3833 0 Td
(78)Tj
1.1736 0 Td
(images)Tj
2.9877 0 Td
(from)Tj
2.2053 0 Td
(1)Tj
0.6973 0 Td
(study,)Tj
2.6136 0 Td
(PD)Tj
1.5193 0 Td
(could)Tj
2.4491 0 Td
(be)Tj
1.1509 0 Td
(estimated,)Tj
4.2973 0 Td
(but)Tj
1.5534 0 Td
(uncertainties)Tj
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(in)Tj
1.0375 0 Td
(the)Tj
1.4683 0 Td
(original)Tj
3.3279 0 Td
(pixel)Tj
-35.2344 -1.3039 Td
(size)Tj
1.6837 0 Td
(prevented)Tj
4.2066 0 Td
(the)Tj
1.474 0 Td
(calculation)Tj
4.5751 0 Td
(of)Tj
1.0148 0 Td
(absolute)Tj
3.5206 0 Td
(areas.)Tj
ET
Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 308.0125 cm
BT
/F0 1 Tf
1 TL
-0.0033 Tc
0 0 Td
(Statistical)Tj
4.4504 0 Td
(methods)Tj
ET
Q
q
1 j
1 J
0 w
10 0 0 10 200.0125 291.0047 cm
BT
/F6 1 Tf
1 TL
-0.004 Tc
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1.61 0 Td
(analysed)Tj
3.6453 0 Td
(PD)Tj
1.5194 0 Td
(and)Tj
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(dense,)Tj
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(non-dense,)Tj
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(and)Tj
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(breast)Tj
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(transforming)Tj
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(each)Tj
-34.5597 -1.2982 Td
(measure)Tj
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1.0261 0 Td
(improve)Tj
3.583 0 Td
(normality)Tj
4.1669 0 Td
(of)Tj
1.0148 0 Td
(residuals.)Tj
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1.7858 0 Td
(use)Tj
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(the)Tj
1.4683 0 Td
(square-root)Tj
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(transformation)Tj
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-35.2967 -1.3039 Td
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1.0318 0 Td
(regression)Tj
4.3199 0 Td
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3.1068 0 Td
(means)Tj
2.8063 0 Td
(that)Tj
1.7801 0 Td
(absolute)Tj
3.5206 0 Td
(differences)Tj
4.5694 0 Td
(in)Tj
1.0318 0 Td
(areas)Tj
2.2451 0 Td
(are)Tj
1.4513 0 Td
(smaller)Tj
3.1181 0 Td
(at)Tj
0.9524 0 Td
(the)Tj
1.474 0 Td
(lower)Tj
2.4491 0 Td
(end)Tj
1.7235 0 Td
(of)Tj
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(the)Tj
1.4683 0 Td
(PD)Tj
1.5137 0 Td
(range.)Tj
2.6872 0 Td
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1.6271 0 Td
(example,)Tj
3.7757 0 Td
(an)Tj
1.2019 0 Td
(increase)Tj
3.4752 0 Td
(in)Tj
/F12 1 Tf
0 Tc
1.0318 0.7087 Td
(p)Tj
/F6 1 Tf
-0.004 Tc
0.8561 -0.7087 Td
(PD)Tj
1.5137 0 Td
(from)Tj
2.2053 0 Td
(4)Tj
0.6974 0 Td
(to)Tj
1.0261 0 Td
(5)Tj
0.6916 0 Td
(\(change)Tj
3.3846 0 Td
(in)Tj
/F12 1 Tf
0 Tc
1.0375 0.7087 Td
(p)Tj
/F6 1 Tf
-0.004 Tc
0.8503 -0.7087 Td
(PD)Tj
1.5194 0 Td
(of)Tj
1.0148 0 Td
(1\))Tj
1.0318 0 Td
(is,)Tj
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(on)Tj
1.2755 0 Td
(the)Tj
-34.9622 -1.2983 Td
(original)Tj
3.3278 0 Td
(scale,)Tj
2.3301 0 Td
(an)Tj
1.2018 0 Td
(increase)Tj
3.4753 0 Td
(from)Tj
2.2053 0 Td
(4)Tj
ET
Q
q
1 j
1 J
0 w
7.4999 0 0 6.6659 330.1795 243.4393 cm
BT
/F6 1 Tf
1 TL
-0.0053 Tc
0 0 Td
(2)Tj
ET
Q
q
1 j
1 J
0 w
10 0 0 10 335.9055 239.0173 cm
BT
/F6 1 Tf
1 TL
-0.004 Tc
0 0 Td
(to)Tj
1.0261 0 Td
(5)Tj
ET
Q
q
1 j
1 J
0 w
7.4999 0 0 6.6659 350.9291 243.4393 cm
BT
/F6 1 Tf
1 TL
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1.0205 0 Td
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(30,)Tj
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1 j
1 J
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11.9999 0 0 11.9999 200.0125 399.1748 cm
BT
/F2 1 Tf
1 TL
-0.0033 Tc
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Q
q
1 j
1 J
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10 0 0 10 200.0125 382.2236 cm
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(11,423)Tj
2.8233 0 Td
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1.7688 0 Td
(4.9\))Tj
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(57.5)Tj
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(either)Tj
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3.1578 0 Td
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2.177 0 Td
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0.6973 0 Td
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(S3)Tj
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q
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1 J
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11.9999 0 0 11.9999 200.0125 242.9858 cm
BT
/F0 1 Tf
1 TL
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Q
q
1 j
1 J
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1 TL
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[()]TJ
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Q
q
1 j
1 J
0 w
7.4999 0 0 6.6659 206.7023 217.4173 cm
BT
/F6 1 Tf
1 TL
-0.0053 Tc
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(2)Tj
ET
Q
q
1 j
1 J
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BT
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1 TL
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(16.5%\))Tj
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[()]TJ
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Q
q
1 j
1 J
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7.4999 0 0 6.6659 299.1685 217.4173 cm
BT
/F6 1 Tf
1 TL
-0.0053 Tc
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(2)Tj
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Q
q
1 j
1 J
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BT
/F6 1 Tf
1 TL
-0.004 Tc
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(=)Tj
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(26.5%\),)Tj
3.1975 0 Td
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(\()Tj
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[()]TJ
ET
Q
q
1 j
1 J
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7.4999 0 0 6.6659 396.17 217.4173 cm
BT
/F6 1 Tf
1 TL
-0.0053 Tc
0 0 Td
(2)Tj
ET
Q
q
1 j
1 J
0 w
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BT
/F6 1 Tf
1 TL
-0.004 Tc
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(=)Tj
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(0%\),)Tj
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[()]TJ
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1 j
1 J
0 w
7.4999 0 0 6.6659 499.1244 217.4173 cm
BT
/F6 1 Tf
1 TL
-0.0053 Tc
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(2)Tj
ET
Q
q
1 j
1 J
0 w
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BT
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1 TL
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(=)Tj
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(0%\))Tj
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(premenopausal)Tj
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(slightly)Tj
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(larger)Tj
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(breast)Tj
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(area.)Tj
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(differences)Tj
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(did)Tj
-35.1266 -1.2983 Td
(not)Tj
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(ASR)Tj
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(category)Tj
3.5943 0 Td
(\()Tj
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(Fig)Tj
1.8199 0 Td
(2A)Tj
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(;)Tj
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1.6044 0 Td
[()]TJ
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0.6973 0 Td
(=)Tj
0.7993 0 Td
(0.31)Tj
1.8709 0 Td
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(PD\).)Tj
2.0806 0 Td
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1.7801 0 Td
(findings)Tj
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(pooled)Tj
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(analyses)Tj
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(closely)Tj
2.8799 0 Td
(matched)Tj
3.6737 0 Td
(the)Tj
1.474 0 Td
(meta-analytic)Tj
5.6523 0 Td
(results,)Tj
3.033 0 Td
(but)Tj
1.5534 0 Td
(confidence)Tj
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(intervals)Tj
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(\(CIs\))Tj
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(were)Tj
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(narrower)Tj
-30.8746 -1.3039 Td
(\(Tables)Tj
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3.1407 0 Td
(2)Tj
0 g
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382.8294 320.8904 m
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f*
421.9002 342.8904 m
421.9002 320.8904 l
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f*
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f*
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f*
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f*
498.5433 342.8904 m
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498.0433 320.8904 l
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f*
498.0433 320.8904 m
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f*
536.8652 342.8904 m
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536.3651 342.8904 l
f*
536.3651 320.8904 m
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536.3651 321.3904 l
f*
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229.0448 298.8904 l
229.0448 320.8904 l
f*
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f*
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0.83 0.64 0.02 0 k
36 192.0756 m
189.0142 192.0756 l
h
f*
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1 TL
-0.005 Tc
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(Table)Tj
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(1.)Tj
1.2614 0 Td
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(istics)Tj
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(raphy)Tj
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(5054)Tj
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(139)Tj
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(159)Tj
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(251)Tj
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(34)Tj
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(29)Tj
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(423)Tj
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(516)Tj
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(244)Tj
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(49)Tj
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(74)Tj
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(476)Tj
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(896)Tj
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(1288)Tj
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(844)Tj
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(647)Tj
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(345)Tj
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(69)Tj
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(4,639)Tj
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(17)Tj
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(135)Tj
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(155)Tj
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(286)Tj
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(310)Tj
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(219)Tj
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(52)Tj
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(7)Tj
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(Hawaiian)Tj
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(121)Tj
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(134)Tj
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(102)Tj
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(122)Tj
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(51)Tj
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(30)Tj
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(23)Tj
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(1)Tj
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(Asian)Tj
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(119)Tj
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(324)Tj
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(304)Tj
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(400)Tj
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(347)Tj
4.826 0 Td
(216)Tj
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(129)Tj
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(32)Tj
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(42.1)Tj
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(57.1)Tj
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(62.1)Tj
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(66.8)Tj
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(postmeno)Tj
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1 J
0 w
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BT
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1 TL
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ET
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q
1 j
1 J
0 w
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(3.2)Tj
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(5.9)Tj
4.7906 0 Td
(18.5)Tj
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(49.0)Tj
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(49.1)Tj
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(49.1)Tj
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(47.8)Tj
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(48.1)Tj
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(2.2)Tj
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(2.3)Tj
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(2.5)Tj
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(24.0)Tj
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(23.8)Tj
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(24.1)Tj
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(24.3)Tj
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(\(5.2\))Tj
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(HRT)Tj
2.2748 0 Td
(ever)Tj
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(use)Tj
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(5.4)Tj
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(9.3)Tj
4.7906 0 Td
(13.1)Tj
4.819 0 Td
(25.4)Tj
4.8189 0 Td
(32.6)Tj
4.826 0 Td
(34.7)Tj
4.7906 0 Td
(44.0)Tj
4.7906 0 Td
(39.8)Tj
4.7906 0 Td
(24.3)Tj
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(BMI)Tj
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1 j
1 J
0 w
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BT
/F0 1 Tf
1 TL
0 0 Td
()Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 55.3322 433.8708 cm
BT
/F0 1 Tf
1 TL
0 0 Td
(\(kg/m)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 75.2881 437.4425 cm
BT
/F0 1 Tf
1 TL
0 0 Td
(2)Tj
ET
Q
q
1 j
1 J
0 w
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BT
/F0 1 Tf
1 TL
0 0 Td
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(25.5)Tj
0 -1.1834 Td
(\(5.4\))Tj
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(26.2)Tj
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(\(5.3\))Tj
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(26.8)Tj
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(\(5.8\))Tj
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(27.3)Tj
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(\(5.5\))Tj
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(27.2)Tj
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(\(5.2\))Tj
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(27.2)Tj
0 -1.1834 Td
(\(5.4\))Tj
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(27.5)Tj
0 -1.1834 Td
(\(5.6\))Tj
4.7906 1.1834 Td
(26.7)Tj
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(\(5.8\))Tj
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(26.9)Tj
0 -1.1834 Td
(\(5.5\))Tj
/F2 1 Tf
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(Mammo)Tj
3.7559 0 Td
(graphic)Tj
3.8338 0 Td
(measures:)Tj
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(mean)Tj
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(\(SD\))Tj
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(Percent)Tj
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(density)Tj
3.3731 0 Td
(\(%\))Tj
17.5395 0 Td
(29.9)Tj
0 -1.1906 Td
(\(15.4\))Tj
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(27.9)Tj
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(\(15.0\))Tj
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(27.4)Tj
0 -1.1906 Td
(\(15.0\))Tj
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(22.5)Tj
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(\(13.8\))Tj
4.8189 1.1906 Td
(18.7)Tj
0 -1.1906 Td
(\(12.3\))Tj
4.826 1.1906 Td
(16.9)Tj
0 -1.1906 Td
(\(11.8\))Tj
4.7906 1.1906 Td
(16.3)Tj
0 -1.1906 Td
(\(12.3\))Tj
4.7906 1.1906 Td
(17.9)Tj
0 -1.1906 Td
(\(14.9\))Tj
4.7906 1.1906 Td
(22.6)Tj
0 -1.1906 Td
(\(14.4\))Tj
-62.9862 -1.5591 Td
(Dense)Tj
3.0968 0 Td
(area)Tj
2.2111 0 Td
(\(cm)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 91.7858 380.9196 cm
BT
/F0 1 Tf
1 TL
0 0 Td
(2)Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 95.074 377.4047 cm
BT
/F0 1 Tf
1 TL
0 0 Td
(\))Tj
17.1851 0 Td
(37.7)Tj
0 -1.1905 Td
(\(20.9\))Tj
4.7906 1.1905 Td
(37.2)Tj
0 -1.1905 Td
(\(21.3\))Tj
4.7906 1.1905 Td
(36.2)Tj
0 -1.1905 Td
(\(21.6\))Tj
4.8189 1.1905 Td
(31.8)Tj
0 -1.1905 Td
(\(21.2\))Tj
4.819 1.1905 Td
(27.0)Tj
0 -1.1905 Td
(\(18.6\))Tj
4.826 1.1905 Td
(25.0)Tj
0 -1.1905 Td
(\(17.6\))Tj
4.7906 1.1905 Td
(24.2)Tj
0 -1.1905 Td
(\(18.7\))Tj
4.7906 1.1905 Td
(26.5)Tj
0 -1.1905 Td
(\(18.4\))Tj
4.7906 1.1905 Td
(31.3)Tj
0 -1.1905 Td
(\(20.8\))Tj
-62.9863 -1.5591 Td
(Breast)Tj
3.104 0 Td
(area)Tj
2.2181 0 Td
(\(cm)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 91.8425 358.9228 cm
BT
/F0 1 Tf
1 TL
0 0 Td
(2)Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 95.1307 355.4078 cm
BT
/F0 1 Tf
1 TL
0 0 Td
(\))Tj
17.178 0 Td
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