Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test.
Reithinger, Richard;
Grijalva, Mario J;
Chiriboga, Rosa F;
de Noya, Belkisyolé Alarcón;
Torres, Jaime R;
Pavia-Ruz, Norma;
Manrique-Saide, Pablo;
Cardinal, Marta V;
Gürtler, Ricardo E;
(2010)
Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test.
Journal of clinical microbiology, 48 (8).
pp. 3003-3007.
ISSN 0095-1137
DOI: https://doi.org/10.1128/JCM.02474-09
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We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known serological results from Argentina, Ecuador, Mexico, and Venezuela. One hundred forty-nine of 366 (40.7%) and 171/366 (46.7%) samples tested positive by dipstick and serology, respectively. Dipstick sensitivity was calculated to be 84.8% (range between countries, 77.5 to 95%), and specificity was 97.9% (95.9 to 100%).