Items where Author is "Blackman, MJ"
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Number of items: 84.
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Bannister, LH;
Hopkins, JM;
Dluzewski, AR;
Margos, G;
Williams, IT;
Blackman, MJ;
Kocken, CH;
Thomas, AW;
Mitchell, GH;
(2003)
Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development.
Journal of cell science, 116 (Pt 18).
pp. 3825-34.
ISSN 0021-9533
DOI: https://doi.org/10.1242/jcs.00665
Full text not available from this repository.
Blackman, MJ;
(2003)
RNAi in protozoan parasites: what hope for the Apicomplexa?
Protist, 154 (2).
pp. 177-80.
ISSN 1434-4610
DOI: https://doi.org/10.1078/143446103322166482
Full text not available from this repository.
Blackman, MJ;
(2004)
Proteases in host cell invasion by the malaria parasite.
Cellular microbiology, 6 (10).
pp. 893-903.
ISSN 1462-5814
DOI: https://doi.org/10.1111/j.1462-5822.2004.00437.x
Full text not available from this repository.
Blackman, MJ;
Bannister, LH;
(2001)
Apical organelles of Apicomplexa: biology and isolation by subcellular fractionation.
Molecular and biochemical parasitology, 117 (1).
pp. 11-25.
ISSN 0166-6851
DOI: https://doi.org/10.1016/S0166-6851(01)00328-0
Full text not available from this repository.
Blackman, MJ;
Carruthers, VB;
(2013)
Recent insights into apicomplexan parasite egress provide new views to a kill.
Current opinion in microbiology, 16 (4).
pp. 459-64.
ISSN 1369-5274
DOI: https://doi.org/10.1016/j.mib.2013.04.008
Full text not available from this repository.
Blackman, MJ;
Corrie, JE;
Croney, JC;
Kelly, G;
Eccleston, JF;
Jameson, DM;
(2002)
Structural and biochemical characterization of a fluorogenic rhodamine-labeled malarial protease substrate.
Biochemistry, 41 (40).
pp. 12244-52.
ISSN 0006-2960
DOI: https://doi.org/10.1021/bi0263661
Full text not available from this repository.
Blumenschein, TM;
Friedrich, N;
Childs, RA;
Saouros, S;
Carpenter, EP;
Campanero-Rhodes, MA;
Simpson, P;
Chai, W;
Koutroukides, T;
Blackman, MJ;
+3 more...
Feizi, T;
Soldati-Favre, D;
Matthews, S;
(2007)
Atomic resolution insight into host cell recognition by Toxoplasma gondii.
The EMBO journal, 26 (11).
pp. 2808-20.
ISSN 0261-4189
DOI: https://doi.org/10.1038/sj.emboj.7601704
Full text not available from this repository.
Carruthers, VB;
Blackman, MJ;
(2005)
A new release on life: emerging concepts in proteolysis and parasite invasion.
Molecular microbiology, 55 (6).
pp. 1617-30.
ISSN 0950-382X
DOI: https://doi.org/10.1111/j.1365-2958.2005.04483.x
Full text not available from this repository.
Chesne-Seck, ML;
Pizarro, JC;
Vulliez-Le Normand, B;
Collins, CR;
Blackman, MJ;
Faber, BW;
Remarque, EJ;
Kocken, CH;
Thomas, AW;
Bentley, GA;
(2005)
Structural comparison of apical membrane antigen 1 orthologues and paralogues in apicomplexan parasites.
Molecular and biochemical parasitology, 144 (1).
pp. 55-67.
ISSN 0166-6851
DOI: https://doi.org/10.1016/j.molbiopara.2005.07.007
Full text not available from this repository.
Collins, CR;
Blackman, MJ;
(2011)
Apicomplexan AMA1 in host cell invasion: a model at the junction?
Cell host & microbe, 10 (6).
pp. 531-3.
ISSN 1931-3128
DOI: https://doi.org/10.1016/j.chom.2011.11.006
Full text not available from this repository.
Collins, CR;
Withers-Martinez, C;
Bentley, GA;
Batchelor, AH;
Thomas, AW;
Blackman, MJ;
(2007)
Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.
The Journal of biological chemistry, 282 (10).
pp. 7431-41.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M610562200
Full text not available from this repository.
Deligianni, E;
Morgan, RN;
Bertuccini, L;
Wirth, CC;
Silmon de Monerri, NC;
Spanos, L;
Blackman, MJ;
Louis, C;
Pradel, G;
Siden-Kiamos, I;
(2013)
A perforin-like protein mediates disruption of the erythrocyte membrane during egress of Plasmodium berghei male gametocytes.
Cellular microbiology, 15 (8).
pp. 1438-55.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12131
Full text not available from this repository.
Dowse, TJ;
Koussis, K;
Blackman, MJ;
Soldati-Favre, D;
(2008)
Roles of proteases during invasion and egress by Plasmodium and Toxoplasma.
Sub-cellular biochemistry, 47.
pp. 121-39.
ISSN 0306-0225
http://researchonline.lshtm.ac.uk/id/eprint/1544257
Full text not available from this repository.
Ersmark, K;
Feierberg, I;
Bjelic, S;
Hamelink, E;
Hackett, F;
Blackman, MJ;
Hultén, J;
Samuelsson, B;
Aqvist, J;
Hallberg, A;
(2004)
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.
Journal of medicinal chemistry, 47 (1).
pp. 110-22.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030933g
Full text not available from this repository.
Ersmark, K;
Nervall, M;
Hamelink, E;
Janka, LK;
Clemente, JC;
Dunn, BM;
Blackman, MJ;
Samuelsson, B;
Aqvist, J;
Hallberg, A;
(2005)
Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations.
Journal of medicinal chemistry, 48 (19).
pp. 6090-106.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm050463l
Full text not available from this repository.
Fleck, SL;
Birdsall, B;
Babon, J;
Dluzewski, AR;
Martin, SR;
Morgan, WD;
Angov, E;
Kettleborough, CA;
Feeney, J;
Blackman, MJ;
+1 more...
Holder, AA;
(2003)
Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum.
The Journal of biological chemistry, 278 (48).
pp. 47670-7.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M306603200
Full text not available from this repository.
Friedrich, N;
Santos, JM;
Liu, Y;
Palma, AS;
Leon, E;
Saouros, S;
Kiso, M;
Blackman, MJ;
Matthews, S;
Feizi, T;
+1 more...
Soldati-Favre, D;
(2010)
Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by apicomplexan parasites.
The Journal of biological chemistry, 285 (3).
pp. 2064-76.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M109.060988
Full text not available from this repository.
Gemma, S;
Giovani, S;
Brindisi, M;
Tripaldi, P;
Brogi, S;
Savini, L;
Fiorini, I;
Novellino, E;
Butini, S;
Campiani, G;
+2 more...
Penzo, M;
Blackman, MJ;
(2012)
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1.
Bioorganic & medicinal chemistry letters, 22 (16).
pp. 5317-21.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2012.06.023
Full text not available from this repository.
Giovani, S;
Penzo, M;
Brogi, S;
Brindisi, M;
Gemma, S;
Novellino, E;
Savini, L;
Blackman, MJ;
Campiani, G;
Butini, S;
(2014)
Rational design of the first difluorostatone-based PfSUB1 inhibitors.
Bioorganic & medicinal chemistry letters, 24 (15).
pp. 3582-6.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2014.05.044
Full text not available from this repository.
Grüring, C;
Moon, RW;
Lim, C;
Holder, AA;
Blackman, MJ;
Duraisingh, MT;
(2014)
Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research.
Cellular microbiology.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12275
Full text not available from this repository.
Howell, SA;
Hackett, F;
Jongco, AM;
Withers-Martinez, C;
Kim, K;
Carruthers, VB;
Blackman, MJ;
(2005)
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.
Molecular microbiology, 57 (5).
pp. 1342-56.
ISSN 0950-382X
DOI: https://doi.org/10.1111/j.1365-2958.2005.04772.x
Full text not available from this repository.
Howell, SA;
Well, I;
Fleck, SL;
Kettleborough, C;
Collins, CR;
Blackman, MJ;
(2003)
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage.
The Journal of biological chemistry, 278 (26).
pp. 23890-8.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M302160200
Full text not available from this repository.
Howell, SA;
Withers-Martinez, C;
Kocken, CH;
Thomas, AW;
Blackman, MJ;
(2001)
Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1.
The Journal of biological chemistry, 276 (33).
pp. 31311-20.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M103076200
Full text not available from this repository.
Jaudzems, K;
Tars, K;
Maurops, G;
Ivdra, N;
Otikovs, M;
Leitans, J;
Kanepe-Lapsa, I;
Domraceva, I;
Mutule, I;
Trapencieris, P;
+2 more...
Blackman, MJ;
Jirgensons, A;
(2014)
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit.
ACS medicinal chemistry letters, 5 (4).
pp. 373-7.
ISSN 1948-5875
DOI: https://doi.org/10.1021/ml4004952
Full text not available from this repository.
Jean, L;
Hackett, F;
Martin, SR;
Blackman, MJ;
(2003)
Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1.
The Journal of biological chemistry, 278 (31).
pp. 28572-9.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M303827200
Full text not available from this repository.
Jean, L;
Withers-Martinez, C;
Hackett, F;
Blackman, MJ;
(2005)
Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity.
Molecular and biochemical parasitology, 144 (2).
pp. 187-97.
ISSN 0166-6851
DOI: https://doi.org/10.1016/j.molbiopara.2005.07.008
Full text not available from this repository.
Johansson, PO;
Chen, Y;
Belfrage, AK;
Blackman, MJ;
Kvarnström, I;
Jansson, K;
Vrang, L;
Hamelink, E;
Hallberg, A;
Rosenquist, A;
+1 more...
Samuelsson, B;
(2004)
Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs.
Journal of medicinal chemistry, 47 (13).
pp. 3353-66.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm031106i
Full text not available from this repository.
Johansson, PO;
Lindberg, J;
Blackman, MJ;
Kvarnström, I;
Vrang, L;
Hamelink, E;
Hallberg, A;
Rosenquist, A;
Samuelsson, B;
(2005)
Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.
Journal of medicinal chemistry, 48 (13).
pp. 4400-9.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm040884n
Full text not available from this repository.
Kocken, CH;
Withers-Martinez, C;
Dubbeld, MA;
van der Wel, A;
Hackett, F;
Valderrama, A;
Blackman, MJ;
Thomas, AW;
(2002)
High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion.
Infection and immunity, 70 (8).
pp. 4471-6.
ISSN 0019-9567
DOI: https://doi.org/10.1128/IAI.70.8.4471-4476.2002
Full text not available from this repository.
Lazarou, M;
Guevara Patiño, JA;
Jennings, RM;
McIntosh, RS;
Shi, J;
Howell, S;
Cullen, E;
Jones, T;
Adame-Gallegos, JR;
Chappel, JA;
+4 more...
McBride, JS;
Blackman, MJ;
Holder, AA;
Pleass, RJ;
(2009)
Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.
Infection and immunity, 77 (12).
pp. 5659-67.
ISSN 0019-9567
DOI: https://doi.org/10.1128/IAI.00167-09
Full text not available from this repository.
Miller, SA;
Binder, EM;
Blackman, MJ;
Carruthers, VB;
Kim, K;
(2001)
A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii.
The Journal of biological chemistry, 276 (48).
pp. 45341-8.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M106665200
Full text not available from this repository.
Miller, SA;
Thathy, V;
Ajioka, JW;
Blackman, MJ;
Kim, K;
(2003)
TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase.
Molecular microbiology, 49 (4).
pp. 883-94.
ISSN 0950-382X
DOI: https://doi.org/10.1046/j.1365-2958.2003.03604.x
Full text not available from this repository.
Montero, E;
Gonzalez, LM;
Rodriguez, M;
Oksov, Y;
Blackman, MJ;
Lobo, CA;
(2006)
A conserved subtilisin protease identified in Babesia divergens merozoites.
The Journal of biological chemistry, 281 (47).
pp. 35717-26.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M604344200
Full text not available from this repository.
Moon, RW;
Hall, J;
Rangkuti, F;
Ho, YS;
Almond, N;
Mitchell, GH;
Pain, A;
Holder, AA;
Blackman, MJ;
(2012)
Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes.
Proceedings of the National Academy of Sciences of the United States of America, 110 (2).
pp. 531-6.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1216457110
Full text not available from this repository.
O'Donnell, RA;
Blackman, MJ;
(2005)
The role of malaria merozoite proteases in red blood cell invasion.
Current opinion in microbiology, 8 (4).
pp. 422-7.
ISSN 1369-5274
DOI: https://doi.org/10.1016/j.mib.2005.06.018
Full text not available from this repository.
Pizarro, JC;
Vulliez-Le Normand, B;
Chesne-Seck, ML;
Collins, CR;
Withers-Martinez, C;
Hackett, F;
Blackman, MJ;
Faber, BW;
Remarque, EJ;
Kocken, CH;
+2 more...
Thomas, AW;
Bentley, GA;
(2005)
Crystal structure of the malaria vaccine candidate apical membrane antigen 1.
Science (New York, NY), 308 (5720).
pp. 408-11.
ISSN 0036-8075
DOI: https://doi.org/10.1126/science.1107449
Full text not available from this repository.
Polson, HE;
Blackman, MJ;
(2005)
A role for poly(dA)poly(dT) tracts in directing activity of the Plasmodium falciparum calmodulin gene promoter.
Molecular and biochemical parasitology, 141 (2).
pp. 179-89.
ISSN 0166-6851
DOI: https://doi.org/10.1016/j.molbiopara.2005.02.008
Full text not available from this repository.
Santos, JM;
Ferguson, DJ;
Blackman, MJ;
Soldati-Favre, D;
(2011)
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.
Science (New York, NY), 331 (6016).
pp. 473-7.
ISSN 0036-8075
DOI: https://doi.org/10.1126/science.1199284
Full text not available from this repository.
Sawmynaden, K;
Saouros, S;
Friedrich, N;
Marchant, J;
Simpson, P;
Bleijlevens, B;
Blackman, MJ;
Soldati-Favre, D;
Matthews, S;
(2008)
Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition.
EMBO reports, 9 (11).
pp. 1149-55.
ISSN 1469-221X
DOI: https://doi.org/10.1038/embor.2008.179
Full text not available from this repository.
Silmon de Monerri, NC;
Flynn, HR;
Campos, MG;
Hackett, F;
Koussis, K;
Withers-Martinez, C;
Skehel, JM;
Blackman, MJ;
(2011)
Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease.
Infection and immunity, 79 (3).
pp. 1086-97.
ISSN 0019-9567
DOI: https://doi.org/10.1128/IAI.00902-10
Full text not available from this repository.
Silvie, O;
Franetich, JF;
Charrin, S;
Mueller, MS;
Siau, A;
Bodescot, M;
Rubinstein, E;
Hannoun, L;
Charoenvit, Y;
Kocken, CH;
+7 more...
Thomas, AW;
Van Gemert, GJ;
Sauerwein, RW;
Blackman, MJ;
Anders, RF;
Pluschke, G;
Mazier, D;
(2004)
A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites.
The Journal of biological chemistry, 279 (10).
pp. 9490-6.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M311331200
Full text not available from this repository.
Wanyiri, JW;
Techasintana, P;
O'Connor, RM;
Blackman, MJ;
Kim, K;
Ward, HD;
(2009)
Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro.
Eukaryotic cell, 8 (4).
pp. 470-7.
ISSN 1535-9778
DOI: https://doi.org/10.1128/EC.00306-08
Full text not available from this repository.
Withers-Martinez, C;
Haire, LF;
Hackett, F;
Walker, PA;
Howell, SA;
Smerdon, SJ;
Dodson, GG;
Blackman, MJ;
(2008)
Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.
Journal of molecular biology, 375 (3).
pp. 773-81.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2007.10.071
Full text not available from this repository.
Withers-Martinez, C;
Jean, L;
Blackman, MJ;
(2004)
Subtilisin-like proteases of the malaria parasite.
Molecular microbiology, 53 (1).
pp. 55-63.
ISSN 0950-382X
DOI: https://doi.org/10.1111/j.1365-2958.2004.04144.x
Full text not available from this repository.
Withers-Martinez, C;
Saldanha, JW;
Ely, B;
Hackett, F;
O'Connor, T;
Blackman, MJ;
(2002)
Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling.
The Journal of biological chemistry, 277 (33).
pp. 29698-709.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M203088200
Full text not available from this repository.
Zhou, XW;
Blackman, MJ;
Howell, SA;
Carruthers, VB;
(2004)
Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex.
Molecular & cellular proteomics, 3 (6).
pp. 565-76.
ISSN 1535-9476
DOI: https://doi.org/10.1074/mcp.M300123-MCP200
Full text not available from this repository.
Public
Benavente, ED;
de Sessions, PF;
Moon, RW;
Grainger, M;
Holder, AA;
Blackman, MJ;
Roper, C;
Drakeley, CJ;
Pain, A;
Sutherland, CJ;
+3 more...
Hibberd, ML;
Campino, S;
Clark, TG;
(2017)
A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line.
International journal for parasitology.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2017.09.008
Blackman, MJ;
(2008)
Malarial proteases and host cell egress: an 'emerging' cascade.
Cellular microbiology, 10 (10).
pp. 1925-34.
ISSN 1462-5814
DOI: https://doi.org/10.1111/j.1462-5822.2008.01176.x
Child, MA;
Epp, C;
Bujard, H;
Blackman, MJ;
(2010)
Regulated maturation of malaria merozoite surface protein-1 is essential for parasite growth.
Molecular microbiology, 78 (1).
pp. 187-202.
ISSN 0950-382X
DOI: https://doi.org/10.1111/j.1365-2958.2010.07324.x
Child, MA;
Harris, PK;
Collins, CR;
Withers-Martinez, C;
Yeoh, S;
Blackman, MJ;
(2013)
Molecular determinants for subcellular trafficking of the malarial sheddase PfSUB2.
Traffic (Copenhagen, Denmark), 14 (10).
pp. 1053-64.
ISSN 1398-9219
DOI: https://doi.org/10.1111/tra.12092
Collins, CR;
Das, S;
Wong, EH;
Andenmatten, N;
Stallmach, R;
Hackett, F;
Herman, JP;
Müller, S;
Meissner, M;
Blackman, MJ;
(2013)
Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle.
Molecular microbiology, 88 (4).
pp. 687-701.
ISSN 0950-382X
DOI: https://doi.org/10.1111/mmi.12206
Collins, CR;
Hackett, F;
Atid, J;
Tan, MSY;
Blackman, MJ;
(2017)
The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes.
PLoS pathogens, 13 (7).
e1006453.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1006453
Collins, CR;
Hackett, F;
Strath, M;
Penzo, M;
Withers-Martinez, C;
Baker, DA;
Blackman, MJ;
(2013)
Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress.
PLoS pathogens, 9 (5).
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1003344
Collins, CR;
Withers-Martinez, C;
Hackett, F;
Blackman, MJ;
(2009)
An inhibitory antibody blocks interactions between components of the malarial invasion machinery.
PLoS pathogens, 5 (1).
e1000273.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1000273
Cruz, LN;
Juliano, MA;
Budu, A;
Juliano, L;
Holder, AA;
Blackman, MJ;
Garcia, CR;
(2012)
Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.
Malar J, 11.
p. 69.
ISSN 1475-2875
DOI: https://doi.org/10.1186/1475-2875-11-69
Das, S;
Hertrich, N;
Perrin, AJ;
Withers-Martinez, C;
Collins, CR;
Jones, ML;
Watermeyer, JM;
Fobes, ET;
Martin, SR;
Saibil, HR;
+4 more...
Wright, GJ;
Treeck, M;
Epp, C;
Blackman, MJ;
(2015)
Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs.
Cell host & microbe, 18 (4).
pp. 433-44.
ISSN 1931-3128
DOI: https://doi.org/10.1016/j.chom.2015.09.007
Deligianni, E;
Silmon de Monerri, NC;
McMillan, PJ;
Bertuccini, L;
Superti, F;
Manola, M;
Spanos, L;
Louis, C;
Blackman, MJ;
Tilley, L;
+1 more...
Siden-Kiamos, I;
(2018)
Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage.
PloS one, 13 (8).
e0201651.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0201651
Diez Benavente, E;
Florez de Sessions, P;
Moon, RW;
Holder, AA;
Blackman, MJ;
Roper, C;
Drakeley, CJ;
Pain, A;
Sutherland, CJ;
Hibberd, ML;
+2 more...
Campino, S;
Clark, TG;
(2017)
Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations.
PLoS genetics, 13 (9).
e1007008.
ISSN 1553-7390
DOI: https://doi.org/10.1371/journal.pgen.1007008
Fulle, S;
Withers-Martinez, C;
Blackman, MJ;
Morris, GM;
Finn, PW;
(2013)
Molecular Determinants of Binding to the Plasmodium Subtilisin-like Protease 1.
Journal of chemical information and modeling, 53 (3).
pp. 573-83.
ISSN 1549-9596
DOI: https://doi.org/10.1021/ci300581z
Hale, VL;
Watermeyer, JM;
Hackett, F;
Vizcay-Barrena, G;
van Ooij, C;
Thomas, JA;
Spink, MC;
Harkiolaki, M;
Duke, E;
Fleck, RA;
+2 more...
Blackman, MJ;
Saibil, HR;
(2017)
Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1619441114
Harris, PK;
Yeoh, S;
Dluzewski, AR;
O'Donnell, RA;
Withers-Martinez, C;
Hackett, F;
Bannister, LH;
Mitchell, GH;
Blackman, MJ;
(2005)
Molecular identification of a malaria merozoite surface sheddase.
PLoS pathogens, 1 (3).
pp. 241-51.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.0010029
Herman, LS;
Fornace, K;
Phelan, J;
Grigg, MJ;
Anstey, NM;
William, T;
Moon, RW;
Blackman, MJ;
Drakeley, CJ;
Tetteh, KKA;
(2018)
Identification and validation of a novel panel of Plasmodium knowlesi biomarkers of serological exposure.
PLoS neglected tropical diseases, 12 (6).
e0006457.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0006457
Hill, RJ;
Ringel, A;
Knuepfer, E;
Moon, RW;
Blackman, MJ;
van Ooij, C;
(2016)
Regulation and essentiality of the START-domain-containing phospholipid transfer protein PFA0210c in malaria parasites.
The Journal of biological chemistry, 291 (46).
pp. 24280-24292.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M116.740506
Jones, ML;
Das, S;
Belda, H;
Collins, CR;
Blackman, MJ;
Treeck, M;
(2016)
A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum.
Scientific reports, 6.
p. 21800.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep21800
Kher, SS;
Penzo, M;
Fulle, S;
Finn, PW;
Blackman, MJ;
Jirgensons, A;
(2014)
Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1.
Bioorganic & medicinal chemistry letters.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2014.07.086
Koussis, K;
Withers-Martinez, C;
Yeoh, S;
Child, M;
Hackett, F;
Knuepfer, E;
Juliano, L;
Woehlbier, U;
Bujard, H;
Blackman, MJ;
(2009)
A multifunctional serine protease primes the malaria parasite for red blood cell invasion.
The EMBO journal, 28 (6).
pp. 725-35.
ISSN 0261-4189
DOI: https://doi.org/10.1038/emboj.2009.22
Moon, RW;
Sharaf, H;
Hastings, CH;
Ho, YS;
Nair, MB;
Rchiad, Z;
Knuepfer, E;
Ramaprasad, A;
Mohring, F;
Amir, A;
+7 more...
Yusuf, NA;
Hall, J;
Almond, N;
Lau, YL;
Pain, A;
Blackman, MJ;
Holder, AA;
(2016)
Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1522469113
O'Donnell, RA;
Hackett, F;
Howell, SA;
Treeck, M;
Struck, N;
Krnajski, Z;
Withers-Martinez, C;
Gilberger, TW;
Blackman, MJ;
(2006)
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.
The Journal of cell biology, 174 (7).
pp. 1023-33.
ISSN 0021-9525
DOI: https://doi.org/10.1083/jcb.200604136
Olivieri, A;
Collins, CR;
Hackett, F;
Withers-Martinez, C;
Marshall, J;
Flynn, HR;
Skehel, JM;
Blackman, MJ;
(2011)
Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies.
PLoS pathogens, 7 (12).
e1002448.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1002448
Perrin, AJ;
Collins, CR;
Russell, MRG;
Collinson, LM;
Baker, DA;
Blackman, MJ;
(2018)
The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress.
mBio, 9 (4).
ISSN 2150-7511
DOI: https://doi.org/10.1128/mBio.00905-18
Pieperhoff, MS;
Pall, GS;
Jiménez-Ruiz, E;
Das, S;
Melatti, C;
Gow, M;
Wong, EH;
Heng, J;
Müller, S;
Blackman, MJ;
+1 more...
Meissner, M;
(2015)
Conditional U1 Gene Silencing in Toxoplasma gondii.
PloS one, 10 (6).
e0130356.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0130356
Pino, P;
Caldelari, R;
Mukherjee, B;
Vahokoski, J;
Klages, N;
Maco, B;
Collins, CR;
Blackman, MJ;
Kursula, I;
Heussler, V;
+2 more...
Brochet, M;
Soldati-Favre, D;
(2017)
A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress.
Technical Report.
American Association for the Advancement of Science.
DOI: https://doi.org/10.1126/science.aaf8675
Ruecker, A;
Shea, M;
Hackett, F;
Suarez, C;
Hirst, EM;
Milutinovic, K;
Withers-Martinez, C;
Blackman, MJ;
(2012)
Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte.
The Journal of biological chemistry, 287 (45).
pp. 37949-63.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M112.400820
Sherling, ES;
Knuepfer, E;
Brzostowski, JA;
Miller, LH;
Blackman, MJ;
van Ooij, C;
(2017)
The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake.
eLife, 6.
ISSN 2050-084X
DOI: https://doi.org/10.7554/eLife.23239
Stallmach, R;
Kavishwar, M;
Withers-Martinez, C;
Hackett, F;
Collins, CR;
Howell, SA;
Yeoh, S;
Knuepfer, E;
Atid, AJ;
Holder, AA;
+1 more...
Blackman, MJ;
(2015)
Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle.
Molecular microbiology, 96 (2).
pp. 368-87.
ISSN 0950-382X
DOI: https://doi.org/10.1111/mmi.12941
Suarez, C;
Volkmann, K;
Gomes, AR;
Billker, O;
Blackman, MJ;
(2013)
The malarial serine protease SUB1 plays an essential role in parasite liver stage development.
PLoS pathogens, 9 (12).
e1003811.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1003811
Thomas, JA;
Collins, CR;
Das, S;
Hackett, F;
Graindorge, A;
Bell, D;
Deu, E;
Blackman, MJ;
(2016)
Development and Application of a Simple Plaque Assay for the Human Malaria Parasite Plasmodium falciparum.
PloS one, 11 (6).
e0157873.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0157873
Thomas, JA;
Tan, MYS;
Bisson, C;
Borg, A;
Umrekar, TR;
Hackett, F;
Hale, VL;
Vizcay-Barrena, G;
Fleck, RA;
Snijders, AP;
+2 more...
Saibil, HR;
Blackman, MJ;
(2018)
A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.
Nature microbiology.
ISSN 2058-5276
DOI: https://doi.org/10.1038/s41564-018-0111-0
Watermeyer, JM;
Hale, VL;
Hackett, F;
Clare, DK;
Cutts, EE;
Vakonakis, I;
Fleck, RA;
Blackman, MJ;
Saibil, HR;
(2015)
A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes.
Blood, 127 (3).
pp. 343-351.
ISSN 0006-4971
DOI: https://doi.org/10.1182/blood-2015-10-674002
Withers-Martinez, C;
Strath, M;
Hackett, F;
Haire, LF;
Howell, SA;
Walker, PA;
Christodoulou, E;
Evangelos, C;
Dodson, GG;
Blackman, MJ;
(2014)
The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Nature communications, 5.
p. 3726.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms4726
Withers-Martinez, C;
Suarez, C;
Fulle, S;
Kher, S;
Penzo, M;
Ebejer, JP;
Koussis, K;
Hackett, F;
Jirgensons, A;
Finn, P;
+1 more...
Blackman, MJ;
(2012)
Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.
International journal for parasitology, 42 (6).
pp. 597-612.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2012.04.005
Woehlbier, U;
Epp, C;
Hackett, F;
Blackman, MJ;
Bujard, H;
(2010)
Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasion.
Malar J, 9.
p. 77.
ISSN 1475-2875
DOI: https://doi.org/10.1186/1475-2875-9-77
Yeoh, S;
O'Donnell, RA;
Koussis, K;
Dluzewski, AR;
Ansell, KH;
Osborne, SA;
Hackett, F;
Withers-Martinez, C;
Mitchell, GH;
Bannister, LH;
+3 more...
Bryans, JS;
Kettleborough, CA;
Blackman, MJ;
(2007)
Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes.
Cell, 131 (6).
pp. 1072-83.
ISSN 0092-8674
DOI: https://doi.org/10.1016/j.cell.2007.10.049
van Ooij, C;
Withers-Martinez, C;
Ringel, A;
Cockcroft, S;
Haldar, K;
Blackman, MJ;
(2013)
Identification of a Plasmodium falciparum phospholipid transfer protein.
The Journal of biological chemistry, 288 (44).
pp. 31971-83.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M113.474189