Items where Author is "Yardley, V"
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Number of items: 32.
2018
Guo, M;
Wang, K;
Qiao, N;
Yardley, V;
Li, M;
(2018)
Investigating Permeation Behavior of Flufenamic Acid Cocrystals Using a Dissolution and Permeation System.
Molecular pharmaceutics.
ISSN 1543-8384
DOI: https://doi.org/10.1021/acs.molpharmaceut.8b00670
Thompson, AM;
O'Connor, PD;
Marshall, AJ;
Blaser, A;
Yardley, V;
Maes, L;
Gupta, S;
Launay, D;
Braillard, S;
Chatelain, E;
+5 more...
Wan, B;
Franzblau, SG;
Ma, Z;
Cooper, CB;
Denny, WA;
(2018)
Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.
Journal of medicinal chemistry.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b01581
Van Bocxlaer, K;
Gaukel, E;
Hauser, D;
Park, SH;
Schock, S;
Yardley, V;
Randolph, R;
Plattner, JJ;
Merchant, T;
Croft, SL;
+2 more...
Jacobs, RT;
Wring, SA;
(2018)
Topical treatment for cutaneous leishmaniasis - dermato-pharmacokinetic led optimisation of benzoxaboroles.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.02419-17
Wijnant, GJ;
Van Bocxlaer, K;
Fortes Francisco, A;
Yardley, V;
Harris, A;
Alavijeh, M;
Murdan, S;
Croft, SL;
(2018)
Local skin inflammation in cutaneous leishmaniasis as a source of variable pharmacokinetics and therapeutic efficacy of liposomal amphotericin B.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00631-18
Wijnant, GJ;
Van Bocxlaer, K;
Yardley, V;
Harris, A;
Alavijeh, M;
Silva-Pedrosa, R;
Antunes, S;
Mauricio, I;
Murdan, S;
Croft, SL;
(2018)
Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome® and AmBisome® in murine cutaneous leishmaniasis.
International journal for parasitology Drugs and drug resistance, 8 (2).
pp. 223-228.
ISSN 2211-3207
DOI: https://doi.org/10.1016/j.ijpddr.2018.04.001
Yardley, V;
Koniordou, M;
(2018)
Chapter 4: Drug Assay Methodology in Leishmaniasis: From the Microplate to Image Analysis.
In: UNSPECIFIED, (ed.)
Drug Discovery for Leishmaniasis.
Royal Society of Chemistry, pp. 55-76.
ISBN 9781782628897
DOI: https://doi.org/10.1039/9781788010177
Full text not available from this repository.
2017
Basilico, N;
Parapini, S;
Sparatore, A;
Romeo, S;
Misiano, P;
Vivas, L;
Yardley, V;
Croft, SL;
Habluetzel, A;
Lucantoni, L;
+8 more...
Renia, L;
Russell, B;
Suwanarusk, R;
Nosten, F;
Dondio, G;
Bigogno, C;
Jabes, D;
Taramelli, D;
(2017)
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.
Molecules (Basel, Switzerland), 22 (12).
ISSN 1420-3049
DOI: https://doi.org/10.3390/molecules22122102
Bhambra, AS;
Ruparelia, KC;
Tan, HL;
Tasdemir, D;
Burrell-Saward, H;
Yardley, V;
Beresford, KJ;
Arroo, RR;
(2017)
Synthesis and antitrypanosomal activities of novel pyridylchalcones.
European journal of medicinal chemistry, 128.
pp. 213-218.
ISSN 0223-5234
DOI: https://doi.org/10.1016/j.ejmech.2017.01.027
Thompson, AM;
O'Connor, PD;
Marshall, AJ;
Yardley, V;
Maes, L;
Gupta, S;
Launay, D;
Braillard, S;
Chatelain, E;
Franzblau, SG;
+5 more...
Wan, B;
Wang, Y;
Ma, Z;
Cooper, CB;
Denny, WA;
(2017)
7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis.
Journal of medicinal chemistry, 60 (10).
pp. 4212-4233.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00034
Wijnant, GJ;
Van Bocxlaer, K;
Yardley, V;
Harris, A;
Murdan, S;
Croft, SL;
(2017)
AmBisome® treatment of murine cutaneous leishmaniasis: relation between skin pharmacokinetics and efficacy.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.02009-17
Wijnant, GJ;
Van Bocxlaer, K;
Yardley, V;
Murdan, S;
Croft, S;
(2017)
Efficacy of a Paromomycin plus Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00358-17
2016
Daunes, S;
Yardley, V;
Croft, SL;
D'Silva, C;
(2016)
Antiprotozoal glutathione derivatives with flagellar membrane binding activity against T. brucei rhodesiense.
Bioorganic & medicinal chemistry.
ISSN 0968-0896
DOI: https://doi.org/10.1016/j.bmc.2016.12.016
Khan, NH;
Bari, AU;
Hashim, R;
Khan, I;
Muneer, A;
Shah, A;
Wahid, S;
Yardley, V;
O'Neil, B;
Sutherland, CJ;
(2016)
Cutaneous Leishmaniasis in Khyber Pakhtunkhwa Province of Pakistan: Clinical Diversity and Species-Level Diagnosis.
The American journal of tropical medicine and hygiene.
ISSN 0002-9637
DOI: https://doi.org/10.4269/ajtmh.16-0343
Tegazzini, D;
Díaz, R;
Aguilar, F;
Peña, I;
Presa, JL;
Yardley, V;
Martin, JJ;
Coteron, JM;
Croft, SL;
Cantizani, J;
(2016)
A replicative in vitro assay for drug discovery against Leishmania donovani.
Antimicrobial agents and chemotherapy, 60 (6).
pp. 3524-32.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.01781-15
Thompson, AM;
O'Connor, PD;
Blaser, A;
Yardley, V;
Maes, L;
Gupta, S;
Launay, D;
Martin, D;
Franzblau, SG;
Wan, B;
+3 more...
Wang, Y;
Ma, Z;
Denny, WA;
(2016)
Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis.
Journal of medicinal chemistry.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.5b01699
Van Bocxlaer, K;
Yardley, V;
Murdan, S;
Croft, SL;
(2016)
Topical formulations of miltefosine for cutaneous leishmaniasis in a BALB/c mouse model.
The Journal of pharmacy and pharmacology, 68 (7).
pp. 862-72.
ISSN 0022-3573
DOI: https://doi.org/10.1111/jphp.12548
Van Bocxlaer, K;
Yardley, V;
Murdan, S;
Croft, SL;
(2016)
Drug permeation and barrier damage in Leishmania-infected mouse skin.
The Journal of antimicrobial chemotherapy, 71 (6).
pp. 1578-85.
ISSN 0305-7453
DOI: https://doi.org/10.1093/jac/dkw012
Full text not available from this repository.
Yizengaw, E;
Getahun, M;
Tajebe, F;
Cruz Cervera, E;
Adem, E;
Mesfin, G;
Hailu, A;
Van der Auwera, G;
Yardley, V;
Lemma, M;
+10 more...
Skhedy, Z;
Diro, E;
Yeshanew, A;
Melkamu, R;
Mengesha, B;
Modolell, M;
Munder, M;
Müller, I;
Takele, Y;
Kropf, P;
(2016)
Visceral Leishmaniasis Patients Display Altered Composition and Maturity of Neutrophils as well as Impaired Neutrophil Effector Functions.
Frontiers in immunology, 7.
p. 517.
ISSN 1664-3224
DOI: https://doi.org/10.3389/fimmu.2016.00517
2015
Bhambra, AS;
Edgar, M;
Elsegood, MR;
Li, Y;
Weaver, GW;
Arroo, RR;
Yardley, V;
Burrell-Saward, H;
Krystof, V;
(2015)
Design, synthesis and antitrypanosomal activities of 2,6-disubstituted-4,5,7-trifluorobenzothiophenes.
European journal of medicinal chemistry, 108.
pp. 347-353.
ISSN 0223-5234
DOI: https://doi.org/10.1016/j.ejmech.2015.11.043
Full text not available from this repository.
Carvalho, L;
Martínez-García, M;
Pérez-Victoria, I;
Manzano, JI;
Yardley, V;
Gamarro, F;
Pérez-Victoria, JM;
(2015)
The oral antimalarial drug tafenoquine shows activity against Trypanosoma brucei.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00879-15
Full text not available from this repository.
2014
Corware, K;
Yardley, V;
Mack, C;
Schuster, S;
Al-Hassi, H;
Herath, S;
Bergin, P;
Modolell, M;
Munder, M;
Müller, I;
+1 more...
Kropf, P;
(2014)
Protein energy malnutrition increases arginase activity in monocytes and macrophages.
Nutrition & metabolism, 11 (1).
p. 51.
ISSN 1743-7075
DOI: https://doi.org/10.1186/1743-7075-11-51
Gupta, S;
Yardley, V;
Vishwakarma, P;
Shivahare, R;
Sharma, B;
Launay, D;
Martin, D;
Puri, SK;
(2014)
Nitroimidazo-oxazole compound DNDI-VL-2098: an orally effective preclinical drug candidate for the treatment of visceral leishmaniasis.
The Journal of antimicrobial chemotherapy.
ISSN 0305-7453
DOI: https://doi.org/10.1093/jac/dku422
Full text not available from this repository.
Les, KA;
Mohamed-Ahmed, AHA;
Balan, S;
Choi, J.-, W;
Martin, D;
Yardley, V;
Powell, K;
Godwin, A;
Brocchini, S;
(2014)
Poly(methacrylic acid) complexation of amphotericin B to treat neglected diseases.
Polymer chemistry, 5 (3).
pp. 1037-1048.
ISSN 1759-9954
DOI: https://doi.org/10.1039/c3py01051a
Full text not available from this repository.
Sanderson, L;
Yardley, V;
Croft, SL;
(2014)
Activity of anti-cancer protein kinase inhibitors against Leishmania spp.
The Journal of antimicrobial chemotherapy.
ISSN 0305-7453
DOI: https://doi.org/10.1093/jac/dku069
Full text not available from this repository.
2008
Decuypere, S;
Vanaerschot, M;
Rijal, S;
Yardley, V;
Maes, L;
de Doncker, S;
Chappuis, F;
Dujardin, JC;
(2008)
Gene expression profiling of Leishmania (Leishmania) donovani: overcoming technical variation and exploiting biological variation.
Parasitology, 135 (2).
pp. 183-194.
ISSN 0031-1820
DOI: https://doi.org/10.1017/S0031182007003782
Fattorusso, C;
Campiani, G;
Kukreja, G;
Persico, M;
Butini, S;
Romano, MP;
Altarelli, M;
Rost, S;
Brindisi, M;
Savini, L;
+10 more...
Novellino, E;
Nacci, V;
Fattorusso, E;
Parapini, S;
Basilico, N;
Taramelli, D;
Yardley, V;
Croft, S;
Borriello, M;
Gemma, S;
(2008)
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.
Journal of medicinal chemistry, 51 (5).
pp. 1333-1343.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm7012375
Full text not available from this repository.
2006
Gemma, S;
Kukreja, G;
Fattorusso, C;
Persico, M;
Romano, MP;
Altarelli, M;
Savini, L;
Campiani, G;
Fattorusso, E;
Basilico, N;
+3 more...
Taramelli, D;
Yardley, V;
Butini, S;
(2006)
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
Bioorganic & medicinal chemistry letters, 16 (20).
pp. 5384-8.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2006.07.060
Full text not available from this repository.
Laurent, T;
Rijal, S;
Yardley, V;
Croft, S;
De Doncker, S;
Decuypere, S;
Khanal, B;
Singh, R;
Schönian, G;
Kuhls, K;
+2 more...
Chappuis, F;
Dujardin, JC;
(2006)
Epidemiological dynamics of antimonial resistance in Leishmania donovani: Genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal.
Infection, genetics and evolution, 7 (2).
pp. 206-12.
ISSN 1567-1348
DOI: https://doi.org/10.1016/j.meegid.2006.08.005
Full text not available from this repository.
Tasdemir, D;
Brun, R;
Yardley, V;
Franzblau, SG;
Rüedi, P;
(2006)
Antituberculotic and antiprotozoal activities of primin, a natural benzoquinone: in vitro and in vivo studies.
Chemistry & biodiversity, 3 (11).
pp. 1230-7.
ISSN 1612-1872
DOI: https://doi.org/10.1002/cbdv.200690124
Full text not available from this repository.
2005
Yardley, V;
Croft, SL;
DE Doncker, S;
Dujardin, JC;
Koirala, S;
Rijal, S;
Miranda, C;
Llanos-Cuentas, A;
Chappuis, F;
(2005)
THE SENSITIVITY OF CLINICAL ISOLATES OF LEISHMANIA FROM PERU AND NEPAL TO MILTEFOSINE.
The American journal of tropical medicine and hygiene, 73 (2).
pp. 272-5.
ISSN 0002-9637
http://researchonline.lshtm.ac.uk/id/eprint/13280
2003
Larabi, M;
Yardley, V;
Loiseau, PM;
Appel, M;
Legrand, P;
Gulik, A;
Bories, C;
Croft, SL;
Barratt, G;
(2003)
Toxicity and Antileishmanial Activity of a New Stable Lipid Suspension of Amphotericin B.
Antimicrobial agents and chemotherapy, 47 (12).
pp. 3774-3779.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.47.12.3774-3779.2003
Full text not available from this repository.
Magaraci, F;
Jimenez, CJ;
Rodrigues, C;
Rodrigues, JCF;
Braga, MV;
Yardley, V;
de Luca-Fradley, K;
Croft, SL;
de Souza, W;
Ruiz-Perez, LM;
+3 more...
Urbina, J;
Pacanowska, DG;
Gilbert, IH;
(2003)
Azasterols as inhibitors of sterol 24-methyltransferase in leishmania species and Trypanosoma cruzi.
Journal of medicinal chemistry, 46 (22).
pp. 4714-4727.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm021114j
Full text not available from this repository.